A review of new developments in the Friedel–Crafts alkylation – From green chemistry to asymmetric catalysis

• Magnus Rueping and
• Boris J. Nachtsheim

Beilstein J. Org. Chem. 2010, 6, No. 6, doi:10.3762/bjoc.6.6

• , only highly reactive ferrocenyl alcohols 29a or benzhydrols 29b–d, which result in highly stabilized carbocations upon elimination, can be used in this procedure (Scheme 13) [50]. An interesting domino reduction–alkylation procedure was recently developed by Peris et al. employing a versatile Ir-Cp

• catalysts are required that stabilize the transient carbocations and are able to mediate enantioselective SN1 reactions. Moreover, Friedel–Crafts alkylations of arenes bearing free amines or nitrogen-containing heterocycles will be a great advance in this area. This increase in functional group tolerance

Allylsilanes in the synthesis of three to seven membered rings: the silylcuprate strategy

• Asunción Barbero,
• Francisco J. Pulido and
• M. Carmen Sañudo

Beilstein J. Org. Chem. 2007, 3, No. 16, doi:10.1186/1860-5397-3-16

• carbocations β to silicon (the so-called β-effect). A unique feature of the reaction is the invariable formation of an exocyclic double bond by loss of the silicon group. The methylenecyclopentanol moiety is present in the skeleton of some naturally occurring terpene families. Recent work has shown that the

Generation of pyridyl coordinated organosilicon cation pool by oxidative Si-Si bond dissociation

• Toshiki Nokami,
• Ryoji Soma,
• Yoshimasa Yamamoto,
• Toshiyuki Kamei,
• Kenichiro Itami and
• Jun-ichi Yoshida

Beilstein J. Org. Chem. 2007, 3, No. 7, doi:10.1186/1860-5397-3-7

• " method, which involves the irreversible oxidative generation and accumulation of highly reactive cations in the absence of nucleophiles [1][2][3][4][5]. Heteroatom-stabilized carbocations, such as N-acyliminium ion pools and alkoxycarbenium ion pools have been generated based on oxidative C-H, C-Si, and

• organosilicon cation 3d and silyl radical 4d by DFT calculations (B3LYP/LANL2DZ). Electrochemical generation of carbocations by oxidative C-C bond dissociation. Electrochemical generation and accumulation of organosilicon cation by oxidative Si-Si bond dissociation. Electrochemical generation of organosilicon