Total synthesis of the indolizidine alkaloid tashiromine

• Stephen P. Marsden and
• Alison D. McElhinney

Beilstein J. Org. Chem. 2008, 4, No. 8, doi:10.1186/1860-5397-4-8

• sidechain found in tashiromine. The synthesis of azabicyclic assemblies by intramolecular allylsilane/N-acyliminium cyclisations was first studied by Hiemstra and Speckamp [16], who prepared their functionalised allylsilane cyclisation precursors (such as 3) by alkylation of cyclic imides with reagent 4 (X