Beilstein J. Org. Chem.2009,5, No. 29, doi:10.3762/bjoc.5.29
become deposited on the catalyst beads on standing between studies and that the initial linear increase in yield was a consequence of the salts being washed off in the continuous flow and adsorption of the organobromide on to the newly freed reactive sites.
It is seen from Figure 6 hat the production of
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Graphical Abstract
Scheme 1:
Synthesis of 4-methoxybiphenyl (4-MeOBP) and by-products in the Kumada reaction.