Diastereoselective functionalisation of benzo-annulated bicyclic sultams: Application for the synthesis of cis-2,4-diarylpyrrolidines

• Susan Kelleher,
• Pierre-Yves Quesne and
• Paul Evans

Beilstein J. Org. Chem. 2009, 5, No. 69, doi:10.3762/bjoc.5.69

• above proving inefficient, palladium chemistry was subsequently considered. The vinyl bromide 24a was reported to participate in Sonagashira alkynylation chemistry; however, yields of the resultant enyne were low [20]. Therefore, we decided to investigate Suzuki–Miyaura cross-coupling reaction as a

• . Possible explanation for the products formed in the dibromination of 5a and 5b. Lithiation–CO2 quench approach for the synthesis of 26 from vinyl bromide 24a. Suzuki–Miyaura cross-coupling of 24a and the diastereoselective hydrogenation of the resultant styrene adducts. Attempted sulfonamide double

Polyionic polymers – heterogeneous media for metal nanoparticles as catalyst in Suzuki–Miyaura and Heck–Mizoroki reactions under flow conditions

• Klaas Mennecke and
• Andreas Kirschning

Beilstein J. Org. Chem. 2009, 5, No. 21, doi:10.3762/bjoc.5.21

• nanoparticles (7–10 nm in size and a palladium content of 0.03 weight% Pd on polyionic polymer). Suzuki–Miyaura cross coupling reactions In our earlier work we showed that these materials are well suited for transfer hydrogenations under flow conditions [23][24]. Recently, the Suzuki–Miyaura reaction and other

• ] these clusters exert pronounced catalytic activity in solution at very low concentrations. This view is further supported by the fact that the catalytic species operating in the present case is able to promote Suzuki–Miyaura cross coupling reactions with aryl bromides while aryl chlorides are not good

• for the generation of metal nanoparticles. The ionic nature of the resin has a positive impact on the stabilization of the Pd species which results in extended use for Suzuki–Miyaura cross coupling reactions as well as Heck reactions without substantial reduction of activity even when solvents such as

Convenient methods for preparing π-conjugated linkers as building blocks for modular chemistry

• Jiří Kulhánek,
• Filip Bureš and
• Miroslav Ludwig

Beilstein J. Org. Chem. 2009, 5, No. 11, doi:10.3762/bjoc.5.11

• ′-bromobiphenyl intermediates necessary for the preparation of 4a–c were synthesized by the Suzuki–Miyaura cross-coupling of 1-bromo-4-iodobenzene with the corresponding boronic acids/esters 1a–c in the yields of 82, 84, and 91%, respectively. A routine procedure involving a lithiation and reaction with

Mechanistic aspects of the isomerization of Z-vinylic tellurides double bonds in the synthesis of potassium Z-vinyltrifluoroborate salts

• Hélio A. Stefani,
• Rafael C. Guadagnin,
• Artur F. Keppler,
• Giancarlo V. Botteselle,
• João V. Comasseto and
• Carlos A. Suganuma

Beilstein J. Org. Chem. 2008, 4, No. 9, doi:10.1186/1860-5397-4-9

• acids and boronate esters are the most commonly used derivatives in Suzuki-Miyaura cross-coupling reactions. Recently, Molander et al. [1] and our group [2] have explored the use of potassium organotrifluoroborate salts as an alternative to the usual organoboron reagents in alkenyl-alkenyl [3], aryl