Do α-acyloxy and α-alkoxycarbonyloxy radicals fragment to form acyl and alkoxycarbonyl radicals?

• Dennis P. Curran and
• Tiffany R. Turner

Beilstein J. Org. Chem. 2006, 2, No. 10, doi:10.1186/1860-5397-2-10

• setting is illustrated in Figure 4. Abstraction of iodine from 11 produces alkyl radical 12, which will rapidly cyclize to give key intermediate α-acyloxy radical 13a or α-alkoxycarbonyloxy radical 13b. Partitioning of 13a,b between bimolecular reduction to give 14a,b and unimolecular fragmentation to