N-acylation of ethanolamine using lipase: a chemoselective catalyst

• Mazaahir Kidwai,
• Roona Poddar and
• Poonam Mothsra

Beilstein J. Org. Chem. 2009, 5, No. 10, doi:10.3762/bjoc.5.10

• Mazaahir Kidwai Roona Poddar Poonam Mothsra Green Chemistry Research Laboratory, Department of Chemistry, University of Delhi, Delhi-110007, India 10.3762/bjoc.5.10 Abstract The N-acylation of ethanolamine (2) with various fatty acids 1a–d and esters of fatty acids 1e–h using Candida antarctica B

• for hazard assessment of a surfactant because degradation often reduces the toxicity of these chemicals [19]. The hydroxy-substituted aliphatic amides 3a–d act as surfactants, synthesized from fatty acids or esters 1a–h and ethanolamine (2) and they are highly acceptable to the environment as they are

• lipase (CAL B Novozym® 435) with fatty acids or esters 1a–h and ethanolamine (2) under simultaneous microwave irradiation. Results and Discussion In the reaction of fatty acids 1a–d or esters of fatty acids 1e–h with ethanolamine (2), two types of acylated products are possible. Out of two possible

Stereoselective synthesis of (2S,3S,4Z)-4-fluoro- 1,3-dihydroxy- 2-(octadecanoylamino)octadec- 4-ene, [(Z)-4-fluoroceramide], and its phase behavior at the air/water interface

• Gergana S. Nikolova and
• Günter Haufe

Beilstein J. Org. Chem. 2008, 4, No. 12, doi:10.3762/bjoc.4.12

• , sphingolipids are crucial e.g. for the function of the skin because they contribute to the formation of the water permeability barrier consisting of a highly organized multilaminar lipid matrix of free fatty acids, cholesterol and ceramides containing additional hydroxyl groups in the sphingosin part and longer

• water permeability barrier consisting of a highly organized multilaminar lipid matrix of free fatty acids, cholesterol and ceramides containing additional hydroxyl groups in the sphingosin part and longer fatty acid amide functions [23]. The function of the additional free OH group seems to be the