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Search for "intramolecular hydrogen bond" in Full Text gives 79 result(s) in Beilstein Journal of Organic Chemistry.

Synthesis and binding studies of two new macrocyclic receptors for the stereoselective recognition of dipeptides

  • Ana Maria Castilla,
  • M. Morgan Conn and
  • Pablo Ballester

Beilstein J. Org. Chem. 2010, 6, No. 5, doi:10.3762/bjoc.6.5

Graphical Abstract
  • macrocycle, also allows for the possibility of binding short amino acid sequences not necessarily located on the edges of larger peptides. Other considerations, apart from preventing intramolecular hydrogen bond formation, related to the use of bis(alanyl)benzophenone rigid linkers include: a) to avoid
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Published 19 Jan 2010

Reactions of glycidyl derivatives with ambident nucleophiles; part 2: amino acid derivatives

  • Gerald Dyker,
  • Andreas Thöne and
  • Gerald Henkel

Beilstein J. Org. Chem. 2007, 3, No. 28, doi:10.1186/1860-5397-3-28

Graphical Abstract
  • from a weak intramolecular hydrogen bond. According to ab initio calculations for cis-9a, (B3LYP, 6-31G*, zero point energy included) this structure is indeed 1.9 kcal/mol more stable than its exo-oriented conformer and 2.2 kcal/mol more stable than its trans-stereoisomer. Conclusion In summary, we
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Published 27 Sep 2007

8-epi-Salvinorin B: crystal structure and affinity at the κ opioid receptor

  • Thomas A. Munro,
  • Katharine K. Duncan,
  • Richard J. Staples,
  • Wei Xu,
  • Lee-Yuan Liu-Chen,
  • Cécile Béguin,
  • William A. Carlezon Jr. and
  • Bruce M. Cohen

Beilstein J. Org. Chem. 2007, 3, No. 1, doi:10.1186/1860-5397-3-1

Graphical Abstract
  • other possible C8/9/12 stereochemistries (trans/anti, trans/syn and cis/syn) – the furan is equatorial in all cases.[17] The rest of the structure is very similar to the crystal structure of 1a.[1] The hydroxyl group participates in an intramolecular hydrogen bond with the ketone (O2-H2···O1, 2.12 Å
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Published 09 Jan 2007

Crystal engineering of analogous and homologous organic compounds: hydrogen bonding patterns in trimethoprim hydrogen phthalate and trimethoprim hydrogen adipate

  • Packianathan Thomas Muthiah,
  • Savarimuthu Francis,
  • Urszula Rychlewska and
  • Beata Warżajtis

Beilstein J. Org. Chem. 2006, 2, No. 8, doi:10.1186/1860-5397-2-8

Graphical Abstract
  • pyrimethamine hydrogen maleate [21] and pyrimethamine hydrogen succinate [21] are isomorphous since the hydrogen succinate is the saturated analogue of hydrogen maleate. The hydrogen succinate ion adopts a folded conformation with an intramolecular hydrogen bond (mimicking the hydrogen maleate ion) leading to
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Published 07 Apr 2006
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