Beilstein J. Org. Chem.2006,2, No. 18, doi:10.1186/1860-5397-2-18
related Baylis-Hillman reaction between p-nitrobenzaldehyde and methylacrylate using the above chiral IL.[25] A slight increase in de (not optimized value) was detected when employing p-methoxyphenyl (Table 3, entry 2, R = p-MeOC6H4). ILs are highly recyclable and do not lose any of their properties even
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Graphical Abstract
Scheme 1:
Asymmetric aza-Diels-Alder reaction of Danishefsky's diene 1 with imines 2.