The use of silicon- based tethers for the Pauson- Khand reaction

• Adrian P. Dobbs,
• Ian J. Miller and
• Saša Martinović

Beilstein J. Org. Chem. 2007, 3, No. 21, doi:10.1186/1860-5397-3-21

• sequences. Recent examples of the use of silicon-containing tethers have centred upon the Diels-Alder reaction,[4][5] radical reactions[6] and olefin metathesis reactions. There have been reports of applying the temporary tethering methodology of silicon species to the P-K reaction, but with limited success

The Elbs and Boyland- Sims peroxydisulfate oxidations

• E. J. Behrman

Beilstein J. Org. Chem. 2006, 2, No. 22, doi:10.1186/1860-5397-2-22

• solvent. The sulfate ester remains in the aqueous phase. Hydrolysis of the sulfate ester in aqueous acid produces the (usually) organic-soluble dihydric phenol. Reactions are usually run at room temperature or below to reduce the incursion of free radical reactions. The rates are rather slow with typical

Do α-acyloxy and α-alkoxycarbonyloxy radicals fragment to form acyl and alkoxycarbonyl radicals?

• Dennis P. Curran and
• Tiffany R. Turner

Beilstein J. Org. Chem. 2006, 2, No. 10, doi:10.1186/1860-5397-2-10

• whether this product arises through a slow radical fragmentation process or an inefficient, chain-breaking oxidative process. Introduction Most organic radical reactions occur through a cascade of two or more individual steps [1][2]. Knowledge of the nature and rates of these steps – in other words, the

• mechanism of the reaction – is of fundamental interest and is also important in synthetic planning. In synthesis, both the generation of the initial radical of the cascade and the removal of the final radical are crucial events [3]. Many useful radical reactions occur through chains that provide a naturally

• have classed as "self-terminating radical reactions" [5][6][7][8][9][10]. For example, addition of broad assortment of oxygen-centered radicals to cyclodecyne 1 provides isomeric ketones 2 (major) and 3 (minor) in variable yields, depending on the specific radical involved and the reaction conditions