Beilstein J. Org. Chem.2006,2, No. 3, doi:10.1186/1860-5397-2-3
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Examples of calculations
The EcoScale evaluations of four important synthetictransformations taken from the recent literature are shown below. Workup involves manipulations in the given order.
The sum of all penalty points is 36 (Table 2), which gives total score of 64 on the EcoScale (an acceptable
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Graphical Abstract
Scheme 1:
Reduction of nitrobenzene to aniline [23]