Multivalent display of the antimicrobial peptides BP100 and BP143

• Imma Güell,
• Rafael Ferre,
• Kasper K. Sørensen,
• Esther Badosa,
• Iteng Ng-Choi,
• Emilio Montesinos,
• Eduard Bardají,
• Lidia Feliu,
• Knud J. Jensen and
• Marta Planas

Beilstein J. Org. Chem. 2012, 8, 2106–2117, doi:10.3762/bjoc.8.237

• (Bruker Daltonics). High-resolution mass spectrometry (HRMS) was recorded on a Bruker MicroToF-Q MALDI instrument by using a hybrid quadrupole time-of-flight mass spectrometer (University of Zaragoza). Circular dichroism (CD) measurements were obtained using a Jasco spectropolarimeter (J-810, Easton, MD

Preparation of mixed trialkyl alkylcarbonate derivatives of etidronic acid via an unusual route

• Petri A. Turhanen,
• Janne Weisell and
• Jouko J. Vepsäläinen

Beilstein J. Org. Chem. 2012, 8, 2019–2024, doi:10.3762/bjoc.8.228

• [32]. Diastereomeric ratios for each of the compounds 3a–d were calculated from the 31P NMR spectrum. Mass spectra were recorded on a quadrupole time-of-flight mass spectrometer by using electrospray ionization (ESI) with positive-ionization mode for compounds 3a–d and 4 and negative for compound 2

Intramolecular bridges formed by photoswitchable click amino acids

• Christian Hoppmann,
• Ronald Kühne and
• Michael Beyermann

Beilstein J. Org. Chem. 2012, 8, 884–889, doi:10.3762/bjoc.8.100

• % trifluoroethanol (pH 7.5). The reaction mixture was exposed to λ = 365 (4 mW/cm2) for 45 min. LC–MS analysis was performed on an ACQUITY UPLC system equipped with a C18 column (3 μm, 2.1 × 30 mm) in combination with an electrospray time-of-flight (ESI–TOF) mass spectrometer (LCT Premier) from Waters. LC conditions

Formation of carbohydrate-functionalised polystyrene and glass slides and their analysis by MALDI-TOF MS

• Martin J. Weissenborn,
• Johannes W. Wehner,
• Christopher J. Gray,
• Robert Šardzík,
• Claire E. Eyers,
• Thisbe K. Lindhorst and
• Sabine L. Flitsch

Beilstein J. Org. Chem. 2012, 8, 753–762, doi:10.3762/bjoc.8.86

• , and have investigated the use of matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF) mass spectrometry (MS) analysis (Figure 1B), which has been highly successful on ligands immobilised on gold plates [10]. MALDI-TOF MS requires an electrically conducting surface and a matrix for

Synthesis of mesomeric betaine compounds with imidazolium-enolate structure

• Nina Gonsior,
• Fabian Mohr and
• Helmut Ritter

Beilstein J. Org. Chem. 2012, 8, 390–397, doi:10.3762/bjoc.8.42

• -time-of-flight mass spectrometry (MALDI-TOF-MS) was performed on a Bruker Ultraflex TOF mass spectrometer. Ions formed with a pulsed nitrogen laser (25 Hz, 337 nm) were accelerated to 25 kV, with the molecular masses being recorded in the linear mode. 2,5-Dihydroxybenzoic acid (DBH) in acetonitrile

Improved syntheses of high hole mobility phthalocyanines: A case of steric assistance in the cyclo-oligomerisation of phthalonitriles

• Daniel J. Tate,
• Rémi Anémian,
• Richard J. Bushby,
• Suwat Nanan,
• Stuart L. Warriner and
• and Benjamin J. Whitaker

Beilstein J. Org. Chem. 2012, 8, 120–128, doi:10.3762/bjoc.8.14

• yield. The phthalocyanine with eight α-isoheptyl substituents gives a high time-of-flight hole mobility of 0.14 cm2·V−1·s−1 within the temperature range of the columnar hexagonal phase, that is 169–189 °C. Keywords: high hole mobility; phthalocyanine; steric assistance; Thorpe–Ingold effect; time-of

• -octaoctylphthalocyanine show good time-of-flight transits for both holes and electrons, together with exceptionally high mobilities (time-of-flight hole mobilities of 0.20 cm2·V−1·s−1 in the Colr phase at 85 °C and 0.10 cm2·V−1·s−1 in the Colh phase at 100 °C; electron mobilities of 0.30 cm2·V−1·s−1 in the Colr phase at

• 85 °C and 0.20 cm2·V−1·s−1 in the Colh phase at 100 °C) [14][15]. Furthermore, this phthalocyanine gives good time-of-flight electron transits even in an ambient atmosphere [15]. As a result, related α-alkylated phthalocyanines are attracting interest for use in organic devices, such as solar cells

Marilones A–C, phthalides from the sponge-derived fungus Stachylidium sp.

• Celso Almeida,
• Stefan Kehraus,
• Miguel Prudêncio and
• Gabriele M. König

Beilstein J. Org. Chem. 2011, 7, 1636–1642, doi:10.3762/bjoc.7.192

• solvent signals with resonances at δH/C 3.35/49.0 for MeOD and δH/C 2.04/29.8 for (CD3)2CO. HRMS–EI were recorded on a Finnigan MAT 95 spectrometer. HRMS–ESI were recorded on a Bruker Daltonik micrOTOF-Q time-of-flight mass spectrometer with ESI source. HPLC was carried out on a system composed of a

Gelation or molecular recognition; is the bis-(α,β-dihydroxy ester)s motif an omnigelator?

• Peter C. Griffiths,
• David W. Knight,
• Ian R. Morgan,
• Amy Ford,
• James Brown,
• Ben Davies,
• Richard K. Heenan,
• Stephen M. King,
• Robert M. Dalgliesh,
• John Tomkinson,
• Stuart Prescott,
• Ralf Schweins and
• Alison Paul

Beilstein J. Org. Chem. 2010, 6, 1079–1088, doi:10.3762/bjoc.6.123

• simplest measure of gelation – that the gel be stable to inversion [3] – was used to quantify the gel–sol behavior. Small-Angle Neutron Scattering (SANS) Small-angle neutron scattering (SANS) measurements were performed on either (a) the fixed-geometry, time-of-flight LOQ diffractometer (ISIS Spallation

Formation of epoxide-amine oligo-adducts as OH-functionalized initiators for the ring-opening polymerization of ε-caprolactone

• Julia Theis and
• Helmut Ritter

Beilstein J. Org. Chem. 2010, 6, 938–944, doi:10.3762/bjoc.6.105

• reaction was carried out under simultaneous cooling with 5 psi of compressed air. The obtained epoxide-amine addition product 4 was characterized by 13C NMR, Fourier transform infrared (FT-IR) spectroscopy and matrix-assisted laser desorption-ionization time-of-flight (MALDI-TOF) mass spectrometry. The

• the midpoint method. The melting point (Tm) values are reported as the average peak maxima of the second and the third heating cycle. Matrix-assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI-TOF MS) was performed on a Bruker Ultraflex TOF mass spectrometer. Ions formed with

Synthesis and crystal structures of multifunctional tosylates as basis for star-shaped poly(2-ethyl-2-oxazoline)s

• Richard Hoogenboom,
• Martin W. M. Fijten,
• Guido Kickelbick and
• Ulrich S. Schubert

Beilstein J. Org. Chem. 2010, 6, 773–783, doi:10.3762/bjoc.6.96

• -of-flight mass spectrometer using the linear mode for operation (positive ion mode; ionization with a 337 nm pulsed nitrogen laser). Elemental analyses were performed on a EuroEA3000 Series EuroVector Elemental Analyzer for CHNS-O. X-ray crystal structures were measured by mounting selected crystals

• pump, a 2414 refractive index detector and a Waters Styragel HT4 column utilizing DMF containing 5 mM NH4PF6 at a flow rate of 0.5 mL/min as eluent and the column oven set to 50 °C (PEG calibration). MALDI-TOF-MS was performed on a Voyager-DE™ PRO Biospectrometry™ Workstation (Applied Biosystems) time

Novel multi-responsive P2VP-block-PNIPAAm block copolymers via nitroxide-mediated radical polymerization

• Cathrin Corten,
• Katja Kretschmer and
• Dirk Kuckling

Beilstein J. Org. Chem. 2010, 6, 756–765, doi:10.3762/bjoc.6.89

• nitroxide terminated polymers were characterized by nuclear magnetic resonance (NMR) spectroscopy, size exclusion chromatography (SEC) and matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). Thermal properties were investigated by the differential scanning

• using PSS ‘GRAM’ columns using a P2VP-calibration. The samples were measured at 50 °C in dimethylacetamide (DMAc) containing 0.42 g/L lithium bromide as mobile phase with a flow rate of 1 mL/min. Matrix assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) was performed on

Calix[4]arene-click-cyclodextrin and supramolecular structures with watersoluble NIPAAM-copolymers bearing adamantyl units: “Rings on ring on chain”

• Bernd Garska,
• Monir Tabatabai and
• Helmut Ritter

Beilstein J. Org. Chem. 2010, 6, 784–788, doi:10.3762/bjoc.6.83

• desorption ionization time of flight mass spectrometry (MALDI-TOF-MS) was performed on a Bruker Ultraflex TOF mass spectrometer. Ions formed with a pulsed nitrogen laser (25 Hz, 337 nm) were accelerated to 25 kV, the molecular masses being recorded in linear mode. 2-(4-Hydroxyphenylazo)benzoic eacid (HABA

Free radical homopolymerization of a vinylferrocene/cyclodextrin complex in water

• Helmut Ritter,
• Beate E. Mondrzik,
• Matthias Rehahn and
• Markus Gallei

Beilstein J. Org. Chem. 2010, 6, No. 60, doi:10.3762/bjoc.6.60

• /ionization-time-of-flight mass spectrometry (MALDITOF-MS) was performed on a Bruker Ultraflex TOF mass spectrometer. Cyclic voltammetry measurements were performed on a simplot instrument with a resolution of <100 pA. Dynamic light scattering (DLS) experiments were carried out with a Malvern HPPS-ET at 25 °C

Synthesis and crossover reaction of TEMPO containing block copolymer via ROMP

• Olubummo Adekunle,
• Susanne Tanner and
• Wolfgang H. Binder

Beilstein J. Org. Chem. 2010, 6, No. 59, doi:10.3762/bjoc.6.59

• desorption ionization time-of-flight) measurements were performed on a Bruker Autoflex-III instrument equipped with a smart ion beam laser. Measurements were carried out in linear and reflector mode. Samples were prepared from THF solution by mixing matrix (20 mg/ml), polymer (20 mg/ml), and salt (20 mg/ml

Self-assembled ordered structures in thin films of HAT5 discotic liquid crystal

• Piero Morales,
• Jan Lagerwall,
• Paolo Vacca,
• Sabine Laschat and
• Giusy Scalia

Beilstein J. Org. Chem. 2010, 6, No. 51, doi:10.3762/bjoc.6.51

• mobility this material is, unlike many other discotic LCs, relatively easy to align uniformly in a homeotropic configuration between two glass plates, thus allowing time-of-flight measurements of photoconductivity. While most of the studies are with such geometry, which is obtained by confining the LC

Templated versus non-templated synthesis of benzo-21-crown-7 and the influence of substituents on its complexing properties

• Wei Jiang and
• Christoph A. Schalley

Beilstein J. Org. Chem. 2010, 6, No. 14, doi:10.3762/bjoc.6.14

• coupling constants (J) are in Hertz. The following abbreviations were used for signal multiplicities: s, singlet; d, doublet; t triplet; m, multiplet. Electrospray-ionization time-of-flight high-resolution mass spectrometry (ESI-TOF-HRMS) experiments were conducted on an Agilent 6210 ESI-TOF, Agilent