Multiple hydride reduction pathways in isoflavonoids

• Auli K. Salakka,
• Tuija H. Jokela and
• Kristiina Wähälä

Beilstein J. Org. Chem. 2006, 2, No. 16, doi:10.1186/1860-5397-2-16

• (Table 3). [16][29][34] Isoflavanones are reduced by electrophilic hydrides (borane-tetrahydrofuran, bis-tert-butylthioethane borane) diastereoselectively to cis-isoflavan-4-ols, but a large excess of the reducing agent is usually needed [29]. Although it was realized by the early workers that