The oxanorbornene approach to 3-hydroxy, 3,4-dihydroxy and 3,4,5-trihydroxy derivatives of 2-aminocyclohexanecarboxylic acid

• Ishmael B. Masesane,
• Andrei S. Batsanov,
• Judith A. K. Howard,
• Raju Mondal and
• Patrick G. Steel

Beilstein J. Org. Chem. 2006, 2, No. 9, doi:10.1186/1860-5397-2-9

• -aminocyclohexanecarboxylic acid. The principal feature of this approach is the reliance on simple reactions exploiting substrate-controlled selectivity. In this respect, the ability of the carbamate group as a directing group is particularly noteworthy. The use of these hydroxylated cyclohexyl β-amino acids in the synthesis