Aroylketene dithioacetal chemistry: facile synthesis of 4-aroyl- 3-methylsulfanyl- 2-tosylpyrroles from aroylketene dithioacetals and TosMIC

• H. Surya Prakash Rao and
• S. Sivakumar

Beilstein J. Org. Chem. 2007, 3, No. 31, doi:10.1186/1860-5397-3-31

• of the cannabinoids. [14] In continuation, and by following the method presently developed, the trisubstituted pyrrole 7 having pyrenoyl substituent was synthesized from AKDTA 6 (Scheme 3). Initially, 1-acetylpyrene 5 was transformed to hitherto unknown pyrene based AKDTA 6 by reaction with carbon

• disulfide and sodium tert-butoxide followed by alkylation with dimethyl sulfate. The reaction of TosMIC 2 with AKDTA 6 provided the trisubstituted pyrrole 7 in excellent yield. As anticipated, the 1H NMR spectrum of pyrenoylpyrrole 7 exhibited a doublet for C2'-H of pyrene unit as a doublet at δ 8.37 ppm

Hydrogen bonding patterns in the cocrystals of 5-nitrouracil with several donor and acceptor molecules

• Reji Thomas,
• R. Srinivasa Gopalan,
• G. U. Kulkarni and
• C. N. R. Rao

Beilstein J. Org. Chem. 2005, 1, No. 15, doi:10.1186/1860-5397-1-15

• ,[19] who reported the formation of pyrene nanorods within a supramolecular framework. 5-nitrouracil, I, is an interesting molecule which can be crystallized in centric and non-centric structures. [21][22] The centric structure obtained by crystallizing I from water, exhibits tapes of nitrouracil