Crystal engineering of analogous and homologous organic compounds: hydrogen bonding patterns in trimethoprim hydrogen phthalate and trimethoprim hydrogen adipate

• Packianathan Thomas Muthiah,
• Savarimuthu Francis,
• Urszula Rychlewska and
• Beata Warżajtis

Beilstein J. Org. Chem. 2006, 2, No. 8, doi:10.1186/1860-5397-2-8

• dihydrate [12], TMP-trifluoroacetate [15], TMP-formate [16], TMP-hydrogen glutarate [17], TMP-nitrate [18], TMP-salicylate methanol solvate [19] etc,. In the crystal structures of TMP-terephthalate-terephthalic acid [13], TMP-3-carboxy-4-hydroxybenzenesulfonate dihydrate [14] and TMP-sulfate trihydrate [20

• structures of trimethoprim-salicylate methanol solvate [18], trimethoprim-trifluoroacetate [15], pyrimethamine-hydrogen phthalate [21] etc,. The characteristic hydrogen-bonded rings observed in the structure aggregate into a supramolecular ladder consisting of a pair of chains, each of which is built up of