The enantiospecific synthesis of (+)-monomorine I using a 5-endo- trig cyclisation strategy

• Malcolm B. Berry,
• Donald Craig,
• Philip S. Jones and
• Gareth J. Rowlands

Beilstein J. Org. Chem. 2007, 3, No. 39, doi:10.1186/1860-5397-3-39

• -mediated hydrolysis led to formation of the N-benzoylaminosulfone 11, presumably by a sequence involving ring-opening by elimination, hydration of the electron-deficient alkenyl sulfone double bond and retro-aldol-like fragmentation. Reductive deprotection proved to be a more fruitful avenue of study