Poly(glycolide) multi-arm star polymers: Improved solubility via limited arm length

• Florian K. Wolf,
• Anna M. Fischer and
• Holger Frey

Beilstein J. Org. Chem. 2010, 6, No. 67, doi:10.3762/bjoc.6.67

• which significantly exceed the molecular weight of processable oligomeric linear PGA (<1000 g/mol). This was achieved by the use of a multifunctional hyperbranched polyglycerol (PG) macroinitiator and the tin(II)-2-ethylhexanoate catalyzed ring-opening polymerization of glycolide in the melt. With this

• architectures exhibit significantly altered physical properties [14][15]. This is often considered the primary motivation for the choice of this interesting polymer architecture [16]. A suitable multifunctional core molecule is required to prepare multi-arm star polymers with core–shell characteristics. Apart

• ][24][25][26] has proven to be a versatile and highly potent multifunctional core molecule [27][28][29]. Derivatization and functionalization of the peripheral hydroxy groups of this polyether-polyol have afforded a number of carrier systems [30][31][32][33][34], matching the concept outlined above. In

RAFT polymers for protein recognition

• Alan F. Tominey,
• Julia Liese,
• Sun Wei,
• Klaus Kowski,
• Thomas Schrader and
• Arno Kraft

Beilstein J. Org. Chem. 2010, 6, No. 66, doi:10.3762/bjoc.6.66

• ]. Rotello and Thayumanavan have described amphiphilic polymer scaffolds, which nonspecifically bound to chymotrypsin, inhibited its peptidase activity and modulated substrate specificity; very high ionic strengths again released the protein from the polymer [6][7]. Protein recognition by multifunctional

New amphiphilic glycopolymers by click functionalization of random copolymers – application to the colloidal stabilisation of polymer nanoparticles and their interaction with concanavalin A lectin

• Otman Otman,
• Paul Boullanger,
• Eric Drockenmuller and
• Thierry Hamaide

Beilstein J. Org. Chem. 2010, 6, No. 58, doi:10.3762/bjoc.6.58

• media. This approach can be easily extended to multifunctional polymer nanoparticles containing encapsulated drugs inside their core. Experimental The syntheses of 8-chloro-3,6-dioxaoctyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranoside (2) and 8-azido-3,6-dioxaoctyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranoside

Synthesis, characterization and photoinduced curing of polysulfones with (meth)acrylate functionalities

• Cemil Dizman,
• Sahin Ates,
• Lokman Torun and
• Yusuf Yagci

Beilstein J. Org. Chem. 2010, 6, No. 56, doi:10.3762/bjoc.6.56

• in detail and covered by several review articles [13][14][15]. Photopolymerization is a frequently used process for the conversion of the multifunctional monomers into insoluble networks which are effective in various industrial fields such as, films, inks, coatings; photoresists, etc. [14]. The

• range capable of inducing rapid polymerization to form insoluble networks [16]. Because of their high reactivity leading to fast polymerization [17], multifunctional (meth)acrylates are the most commonly used monomers for many applications [18][19][20][21][22]. The activity of the (meth)acrylates

Molecular recognition of organic ammonium ions in solution using synthetic receptors

• Andreas Späth and
• Burkhard König

Beilstein J. Org. Chem. 2010, 6, No. 32, doi:10.3762/bjoc.6.32

1-(4-Alkyloxybenzyl)-3-methyl-1H-imidazol-3-ium organic backbone: A versatile smectogenic moiety

• William Dobbs,
• Laurent Douce and
• Benoît Heinrich

Beilstein J. Org. Chem. 2009, 5, No. 62, doi:10.3762/bjoc.5.62

• can impart selectivity in reactions by organising reactants, as scaffolds for the synthesis of nanostructured particles [12][13][14], in dye-sensitized solar cells [15][16] or also in bio-related science [17][18]. In conclusion, this combination represents a fascinating class of new multifunctional

Functional properties of metallomesogens modulated by molecular and supramolecular exotic arrangements

• Alessandra Crispini,
• Mauro Ghedini and
• Daniela Pucci

Beilstein J. Org. Chem. 2009, 5, No. 54, doi:10.3762/bjoc.5.54

• single molecule to supramolecular network, confirming that metal coordination provides a helpful tool for obtaining multifunctional soft materials. Keywords: coordination complexes; functionality; liquid crystals; metallomesogens; Introduction Recent interest in designing novel soft and functional

• the metal ion and the counter-ion in ionic systems, has been followed. In this paper selected examples of recently synthesised multifunctional metallomesogens are highlighted, all obtained from classical and unusual nitrogen ligands and different metal centres from across the periodic table, going

• multifunctional soft materials, with higher performance than classical liquid crystals. Our interest in the synthesis of metallomesogens and their wide use in the field of material science, coupled with the fact that transition metal complexes have potential antitumor activity, led us to believe that a great

Ru-catalyzed dehydrogenative coupling of carboxylic acids and silanes - a new method for the preparation of silyl ester

• Guo-Bin Liu and
• Hong-Yun Zhao

Beilstein J. Org. Chem. 2008, 4, No. 27, doi:10.3762/bjoc.4.27

• ester)s were found to be an ideal family of degradable polymers [1]. Also, multifunctional silyl esters have been found to be ideal cross-linking agents since they require only mild reaction conditions, especially for silicone elastomers. The demand for degradable poly(silyl ester)s has been increasing

Electronic differentiation competes with transition state sensitivity in palladium- catalyzed allylic substitutions

• Dominik A. Lange and
• Bernd Goldfuss

Beilstein J. Org. Chem. 2007, 3, No. 36, doi:10.1186/1860-5397-3-36

• of substrate and catalyst structures. "Side arm guidance" of nucleophiles with multifunctional phosphinoferrocenes [14][15][16][17][18] or "chiral pockets" in C2-symmetric diphosphanes based on 2-(diphenyl-phosphino)benzoic acid amides [19][20][21][22] were applied especially successfully. Chiral P,N

A convenient synthesis of γ-functionalized cyclopentenones

• Nour Lahmar,
• Taïcir Ben Ayed,
• Moncef Bellassoued and
• Hassen Amri

Beilstein J. Org. Chem. 2005, 1, No. 11, doi:10.1186/1860-5397-1-11

• previously reported, the 1,4-addition of primary nitroalkanes [7][8][9][10][11][12] to functionalized α,β-unsaturated ketones was considered as an appropriate method to prepare multifunctional nitroketonic compounds. These intermediates are important in organic synthesis because the nitro group can be