Reduction of arenediazonium salts by tetrakis(dimethylamino)ethylene (TDAE): Efficient formation of products derived from aryl radicals

• Mohan Mahesh,
• John A. Murphy,
• Franck LeStrat and
• Hans Peter Wessel

Beilstein J. Org. Chem. 2009, 5, No. 1, doi:10.3762/bjoc.5.1

• vinblastine (58a) and vincristine (58b) contain such a system. Aryl C-C bond formation As a final extension of this methodology, we probed the feasibility of this methodology in aryl-aryl C-C bond formation reactions. Accordingly, the diazonium salt 62 was prepared from indoline (59), and treated with one

• reaction conditions for greater efficiency. A preliminary study on TDAE-mediated aryl-aryl C-C bond formation reaction has also been discussed. TDAE possesses a distinct advantage over other organic reducing agents as the oxidized products of TDAE are water soluble – thus the purification process is highly

Mixtures of monodentate P-ligands as a means to control the diastereoselectivity in Rh-catalyzed hydrogenation of chiral alkenes

• Manfred T. Reetz and
• Hongchao Guo

Beilstein J. Org. Chem. 2005, 1, No. 3, doi:10.1186/1860-5397-1-3

• using a 1:1 mixture of triphenylphosphine and a certain phosphinine (substituted phospha-benzene), 95% regioselectivity in favor of C-C bond formation at the higher substituted C-atom was achieved, whereas the use of the pure ligands as traditional homo-combinations led to low degrees of