Mixtures of monodentate P-ligands as a means to control the diastereoselectivity in Rh-catalyzed hydrogenation of chiral alkenes

• Manfred T. Reetz and
• Hongchao Guo

Beilstein J. Org. Chem. 2005, 1, No. 3, doi:10.1186/1860-5397-1-3

• catalytic profiles without the need to prepare new ligands. The application of combinatorial chemical methods in asymmetric catalysis has emerged as a promising area of research, and indeed several reviews covering the subject have appeared.[1][2][3][4][5][6][7][8] It is based on the preparation of

Beilstein Journal of Organic Chemistry

• Jonathan Clayden

Beilstein J. Org. Chem. 2005, 1, No. 1, doi:10.1186/1860-5397-1-1

• still to be discovered. Four years ago, the Nobel prize in chemistry celebrated chemists' achievements in asymmetric catalysis – and even since then the face of catalysis is changing, with for example metathesis and organocatalytic methods constantly breaking into new areas. Synthesis is changing too