Variations in product in reactions of naphthoquinone with primary amines

• Marjit W. Singh,
• Anirban Karmakar,
• Nilotpal Barooah and
• Jubaraj B. Baruah

Beilstein J. Org. Chem. 2007, 3, No. 10, doi:10.1186/1860-5397-3-10

• Marjit W. Singh Anirban Karmakar Nilotpal Barooah Jubaraj B. Baruah Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039 Assam, India 10.1186/1860-5397-3-10 Abstract Reaction of 1,2-naphthoquinone with primary amines gives a 2-amino-1,4-naphthoquinone derivative

• -benzoquinone reacts with primary amines to give 2,5-diamino 1,4-benzoquinones; similar reaction of 1,4-naphthoquinone with primary amines results in the formation of 2-amino 1,4-naphthoquinones. [13] However, the product formed from such simple reaction of amine with various quinones has much scope for

• exploration, especially in terms of synthesis of electro/photoactive supramolecular assemblies or polymers. In this communication we describe preliminary account of results obtained on the equivalence of reaction of 1,2-naphthoquinone and 1,4-naphthoquinone with primary amines. Results and discussion It is

Synthesis and glycosidase inhibitory activity of new hexa- substituted C8-glycomimetics

• Olivia Andriuzzi,
• Christine Gravier-Pelletier,
• Gildas Bertho,
• Thierry Prangé and
• Yves Le Merrer

Beilstein J. Org. Chem. 2005, 1, No. 12, doi:10.1186/1860-5397-1-12

• side of the bulky TBDMS group in β-position. However, it has to be pointed out that more hindered nucleophiles, such as primary amines, revealed unable to open the cyclic sulfate 9 or 10. The absolute configurations of 11 and 12 were established by NMR studies. 1H signals were assigned (Table 1) using