Beilstein J. Org. Chem.2005,1, No. 2, doi:10.1186/1860-5397-1-2
(Scheme 2).[24][25][26][27][28][29][30][31][32] Two-directional[33] oxidative ring expansion of 1,3-difuryl 1,3-amino alcohol derivatives 4 would yield a densely functionalised bis-enone which would be ripe for further functionalisation. The term "two-directional synthesis" is usually used to describe the