Cage-like microstructures via sequential Ugi reactions in aqueous emulsions

• Rita S. Alqubelat,
• Yaroslava A. Menzorova and
• Maxim A. Mironov

Beilstein J. Org. Chem. 2024, 20, 2078–2083, doi:10.3762/bjoc.20.179

• . At the first stage, submicron colloidal particles based on carboxymethylcellulose and chitosan with a domain structure were obtained in an aqueous suspension. In the second stage, the Ugi reaction was carried out on the surface of the Pickering emulsions with toluene. Removal of toluene and

• redissolution in water resulted in colloidosomes with large holes on the surface. Varying the cross-link density during the Ugi reaction made it possible to obtain structures with different hole sizes. Keywords: carboxymethylcellulose; chitosan; colloidosomes; Pickering emulsions; Ugi reaction; Introduction

• usually more complex than conventional colloidosomes and involves several stages. Pickering emulsions or polymer spheres coated with a monolayer of colloidal particles are used as initial templates for synthesis [11]. Thus, cage-like structures have been obtained using phase inversion in Pickering

Nanoreactors for green catalysis

• M. Teresa De Martino,
• Loai K. E. A. Abdelmohsen,
• Floris P. J. T. Rutjes and
• Jan C. M. van Hest

Beilstein J. Org. Chem. 2018, 14, 716–733, doi:10.3762/bjoc.14.61

• activity and their performance in incompatible solvents such as water [21][24]. Catalysis in polymersomes: Polymersomes have been most often used as biocatalytic nanoreactors [22][81][82][83]. Polymersome nanoreactors were also employed in Pickering emulsions [83]. Pickering emulsions are emulsions

• ) was encapsulated in the lumen of the polymersomes or in the Pickering emulsion water droplet. The esterification reaction of 1-hexanol and hexanoic acid was used to evaluate the catalytic performance of the CalB-loaded Pickering emulsions. Higher enzymatic activity was observed when CalB was

Heterogeneous Pd catalysts as emulsifiers in Pickering emulsions for integrated multistep synthesis in flow chemistry

• Katharina Hiebler,
• Georg J. Lichtenegger,
• Manuel C. Maier,
• Eun Sung Park,
• Renie Gonzales-Groom,
• Bernard P. Binks and
• Heidrun Gruber-Woelfler

Beilstein J. Org. Chem. 2018, 14, 648–658, doi:10.3762/bjoc.14.52

• , University of Hull, Hull HU6 7RX, UK 10.3762/bjoc.14.52 Abstract Within the “compartmentalised smart factory” approach of the ONE-FLOW project the implementation of different catalysts in “compartments” provided by Pickering emulsions and their application in continuous flow is targeted. We present here the

• used to stabilise Pickering emulsions of oil and water. A set of Ce–Sn–Pd oxides with the molecular formula Ce0.99−xSnxPd0.01O2−δ (x = 0–0.99) has been prepared utilising a simple single-step solution combustion method. The high applicability of the catalysts for different functional groups and their

• . Keywords: compartmentalisation; heterogeneous catalysis; multistep flow chemistry; palladium; Pickering emulsions; Introduction Palladium (Pd) catalysis has been established as a key component in the toolbox of organic chemists. Reactions that are catalysed by palladium benefit from the remarkable

Organic chemistry meets polymers, nanoscience, therapeutics and diagnostics

• Vincent M. Rotello

Beilstein J. Org. Chem. 2016, 12, 1638–1646, doi:10.3762/bjoc.12.161

• area where we demonstrated synergy is in the area of Pickering emulsions. These emulsions are made by interfacial assembly of particles at oil–water interfaces. We showed that nanoparticles and proteins could be self-assembled at this interface [52], retaining their activity. When the oil core was

• cytosol (including materials destined to the nucleus), this entrapment is a major limitation [59]. One of the beauties of supramolecular chemistry is its modularity. We started looking into the use of the Pickering emulsions described above for delivery applications. There was a challenge: nobody

Preparation of Pickering emulsions through interfacial adsorption by soft cyclodextrin nanogels

• Shintaro Kawano,
• Toshiyuki Kida,
• Mitsuru Akashi,
• Hirofumi Sato,
• Motohiro Shizuma and
• Daisuke Ono

Beilstein J. Org. Chem. 2015, 11, 2355–2364, doi:10.3762/bjoc.11.257

• Engineering, Osaka University, Suita, Osaka 565-0871, Japan 10.3762/bjoc.11.257 Abstract Background: Emulsions stabilized by colloidal particles are known as Pickering emulsions. To date, soft microgel particles as well as inorganic and organic particles have been utilized as Pickering emulsifiers. Although

• emulsion; Introduction Pickering emulsions, which are emulsions stabilized by colloidal particles instead of conventional low-molecular-weight surfactants [1], are formed through the adsorption of colloidal particles at an oil–water interface to give stable emulsion droplets. Particle adsorption, which

• the oil–water interfaces that can stabilize emulsions, although they do not alter the surface tension of water alone [15]. Only a few papers have reported Pickering emulsions stabilized by CD inclusion complexes. For example, Inoue et al. prepared oil-in-water (O/W) emulsions with α-, β- and γ-CDs