Sinensiols H–J, three new lignan derivatives from Selaginella sinensis (Desv.) Spring

• Qinfeng Zhu,
• Beibei Gao,
• Qian Chen,
• Tiantian Luo,
• Guobo Xu and
• Shanggao Liao

Beilstein J. Org. Chem. 2022, 18, 1410–1415, doi:10.3762/bjoc.18.146

• , No.132 Lanhei Road, Kunming, 650203, P. R. China 10.3762/bjoc.18.146 Abstract One new lignan sinensiol H (1) and two new bisnorlignans, sinensiols I and J (2 and 3), along with three known compounds were isolated from the whole plants of Selaginella sinensis. Their structures were elucidated on the

• on LPS-induced nitric oxide production in RAW 264.7 macrophages. Keywords: lignan derivatives; nitric oxide production inhibition; norlignans; Selaginella sinensis; Introduction Selaginella is the only genus of Selaginellaceae. As a representative of the earliest and still-surviving vascular plant

• , skin diseases and urinary tract infections [3][4]. In fact, S. tamariscina and S. pulvinata are officially listed in the Chinese Pharmacopoeia for the treatment of amenorrhoea, dysmenorrhoea and traumatic injury [5]. Selaginella sinensis, an endemic species in China, is used as a folk medicine for the