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Search for "angucyclines" in Full Text gives 3 result(s) in Beilstein Journal of Organic Chemistry.

Cofactor-independent C–C bond cleavage reactions catalyzed by the AlpJ family of oxygenases in atypical angucycline biosynthesis

  • Jinmin Gao,
  • Liyuan Li,
  • Shijie Shen,
  • Guomin Ai,
  • Bin Wang,
  • Fang Guo,
  • Tongjian Yang,
  • Hui Han,
  • Zhengren Xu,
  • Guohui Pan and
  • Keqiang Fan

Beilstein J. Org. Chem. 2024, 20, 1198–1206, doi:10.3762/bjoc.20.102

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  • Sciences, No. 1 Yanqihu East Road, Beijing 101408, China State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China 10.3762/bjoc.20.102 Abstract Biosynthesis of atypical angucyclines involves unique oxidative B-ring
  • cofactor-independent manner. Keywords: angucyclines; aromatic polyketide; biosynthesis; cofactor-independent oxygenase; oxidative rearrangement reaction; Introduction The angucyclines represent a large class of natural products biosynthesized by type II polyketide synthases. Within this category, a
  • distinctive subset of compounds, including jadomycin, gilvocarcin, kinamycin, fluostatin, and lomaiviticin, arises from typical angucycline intermediates via oxidative C–C bond cleavage and subsequent ring rearrangement reactions. These atypical angucyclines exhibit intriguing chemical structures and various
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Published 23 May 2024

Synergistic approach to polycycles through Suzuki–Miyaura cross coupling and metathesis as key steps

  • Sambasivarao Kotha,
  • Milind Meshram and
  • Chandravathi Chakkapalli

Beilstein J. Org. Chem. 2018, 14, 2468–2481, doi:10.3762/bjoc.14.223

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  • -dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) to generate nitronaphthalene 15 (60%, Scheme 2). Due to their useful biological activity and intricate structural features of angucyclines such as 16–19 (Figure 2), several approaches have been reported for their assembly. In this context, de Koning and co
  • organic synthesis and green chemistry. Various catalysts used for metathesis reactions. Various angucyclines. SM coupling and RCM protocol to substituted indene derivative 10. Synthesis of polycycles via SM and RCM approach. SM coupling and RCM protocol to the benz[a]anthracene skeleton 26. Synthesis of
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Published 21 Sep 2018

Synthesis of 1,2-cis-2-C-branched aryl-C-glucosides via desulfurization of carbohydrate based hemithioacetals

  • Henok H. Kinfe,
  • Fanuel M. Mebrahtu,
  • Mandlenkosi M. Manana,
  • Kagiso Madumo and
  • Mokela S. Sokamisa

Beilstein J. Org. Chem. 2015, 11, 583–588, doi:10.3762/bjoc.11.64

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  • glycochemistry and medicinal chemistry [1][2][3][4][5]. C-Glycosides, especially aryl-C-glycosides, are the main structural features of a number of biologically active natural products such as pluramycins (antibacterial and antitumor activities), angucyclines (antibacterial, antitumor activities, and inhibitors
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Published 29 Apr 2015
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