Anion–π catalysis on carbon allotropes

• M. Ángeles Gutiérrez López,
• Mei-Ling Tan,
• Giacomo Renno,
• Augustina Jozeliūnaitė,
• J. Jonathan Nué-Martinez,
• Javier Lopez-Andarias,
• Naomi Sakai and
• Stefan Matile

Beilstein J. Org. Chem. 2023, 19, 1881–1894, doi:10.3762/bjoc.19.140

• . Currently, anion–π catalysis on carbon allotropes gains momentum because the combination with electric-field-assisted catalysis promises transformative impact on organic synthesis. Keywords: anion–π interactions; autocatalysis; catalysis; carbon nanotubes; Diels–Alder reactions; electric-field-induced

• tested anion–π catalysts. This result was consistent with the stabilization of the anionic intermediates IX and X and the respective transition states on the polarized fullerene surface. Anion–π autocatalysis on fullerenes The autocatalysis of epoxide-opening ether cyclization on π-acidic aromatic

• surfaces has been identified in 2018 as an emergent property of anion–π catalysis [69]. In this series, fullerene catalyst 31 was found to catalyze the cyclization of epoxide 32 into THF 33 (Figure 6). The rate enhancement for catalysis was 270, whereas autocatalysis accelerated the reaction by 1045 M−1

N-Sulfenylsuccinimide/phthalimide: an alternative sulfenylating reagent in organic transformations

• Fatemeh Doraghi,
• Seyedeh Pegah Aledavoud,
• Mehdi Ghanbarlou,
• Bagher Larijani and
• Mohammad Mahdavi

Beilstein J. Org. Chem. 2023, 19, 1471–1502, doi:10.3762/bjoc.19.106

• basic nature. However, the electron-poor ones exhibited less autocatalysis effect requiring the use of the Lewis base catalyst P. In 2019, Denmark and Panger disclosed a novel method for the preparation of γ‑lactams 133 through the reaction of alkenes 132 with N-thiophthalimides 14 in the presence of

A recursive microfluidic platform to explore the emergence of chemical evolution

• David Doran,
• Marc Rodriguez-Garcia,
• Rebecca Turk-MacLeod,
• Geoffrey J. T. Cooper and
• Leroy Cronin

Beilstein J. Org. Chem. 2017, 13, 1702–1709, doi:10.3762/bjoc.13.164

• : artificial life; autocatalysis; automated platforms; chemical evolution; evolution before genes; evolution first; microfluidics; Introduction The transition from an inanimate inorganic world, principally consisting of minerals, gases and small organic compounds, to the living world with the first life forms

Towards open-ended evolution in self-replicating molecular systems

• Herman Duim and
• Sijbren Otto

Beilstein J. Org. Chem. 2017, 13, 1189–1203, doi:10.3762/bjoc.13.118

• understanding of how life could have emerged from molecular building blocks and what is needed to create a minimal form of life in the laboratory. Keywords: autocatalysis; open-ended evolution; origin of life; self-replication; synthetic life; Introduction Mankind has always pondered upon its own existence

• , when there are virtually no template molecules in the mixture but only building blocks A and B, the bimolecular and binary complex pathways leading to the formation of T and Tinactive will be dominant. Clearly, the inactive template cannot lead to autocatalysis and therefore hinders the self

• -replication process. Upon formation of T, the autocatalytic pathway will become increasingly important, in principle allowing for exponential growth of the template. A requirement for effective autocatalysis, however, is the dissociation of the [T∙T] complex into two individual template molecules. If this