Beilstein J. Org. Chem.2025,21, 839–844, doi:10.3762/bjoc.21.67
catalytic efficiency (up to 99% yield).
Keywords: chitosan-supportedCuIcatalyst; cyclization reaction; mild conditions; quinazolinone; Introduction
Quinazolinones are not only a key core of nitrogen-containing benzo heterocyclic compounds found in many natural products and bioactive molecules [1][2][3
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Graphical Abstract
Scheme 1:
Copper-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazol...