Beilstein J. Org. Chem.2026,22, 480–485, doi:10.3762/bjoc.22.35
domain within the CoREST complex.
Keywords: CI-994; co-repressorcomplex; CoREST; cryo-EM; gold nanoparticle; HDAC; Introduction
Histone deacetylase (HDAC) enzymes catalyze the hydrolysis of acetyl groups from N-acetylated lysine residues in histone proteins. HDACs are also capable of the deacetylation