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Search for "fluorinated amines" in Full Text gives 2 result(s) in Beilstein Journal of Organic Chemistry.

Origami with small molecules: exploiting the C–F bond as a conformational tool

  • Patrick Ryan,
  • Ramsha Iftikhar and
  • Luke Hunter

Beilstein J. Org. Chem. 2025, 21, 680–716, doi:10.3762/bjoc.21.54

Graphical Abstract
  • –C–N alignment is anti, the effect is stronger and the pKaH will be lowered by ≈2 log units. Clearly it is important to bear this in mind when utilising fluorine to optimise the properties of nitrogen-containing drugs. Having concluded our examination of fluorinated amines, let us now focus upon some
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Published 02 Apr 2025

Fluorinated cyclohexanes: Synthesis of amine building blocks of the all-cis 2,3,5,6-tetrafluorocyclohexylamine motif

  • Tetiana Bykova,
  • Nawaf Al-Maharik,
  • Alexandra M. Z. Slawin and
  • David O'Hagan

Beilstein J. Org. Chem. 2017, 13, 728–733, doi:10.3762/bjoc.13.72

Graphical Abstract
  • elimination. The two all-cis tetrafluorocyclohexyl isomers 5a and 5b constitute facially polarized cyclohexane rings, with fluorines on the electronegative face and hydrogens on the electropositive face. Keywords: all-cis tetrafluorocyclohexane motif; deoxofluorination reactions; fluorinated amines
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Published 19 Apr 2017
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