Beilstein J. Org. Chem.2024,20, 1486–1496, doi:10.3762/bjoc.20.132
due to stronger unfavorable entropy, they are in general of lower affinity. The validation of this proof-of-concept and the dissection of thermodynamics of binding will help for the further development of lectin ligands that can be controlled by light.
Keywords: carbohydrates; glycosylazobenzenes
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Graphical Abstract
Figure 1:
(A) Selected monovalent inhibitors for PA LecA and (B) designed general structure of photoswitchabl...