Beilstein J. Org. Chem.2025,21, 845–853, doi:10.3762/bjoc.21.68
separation [4][5][6][7][8]. Building on the extensive research into anion and cation receptors within the realm of supramolecular chemistry [9][10][11][12], numerous heteroditopic ion-pairreceptors have been elaborately developed [13][14][15]. These receptors, consisting of binding sites for both anions and
cations within a single molecule, have facilitated advancements in ion-pair recognition. This progress has led to the development of ion separation utilizing ion-pairreceptors [16][17][18][19][20], which eliminate the need for auxiliary reagents to balance overall charges compared to the use of
individual anion or cation receptors [21]. An alternative approach for ion separation involves the combination of an anion receptor and a cation receptor, known as the dual-host strategy [22][23][24]. Unlike ion-pairreceptors, this strategy avoids the intricate, multi-step synthesis required for designing
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Graphical Abstract
Figure 1:
(a) Schematic illustration of the dual-host strategy for ion pair extraction via solid–liquid metho...
Beilstein J. Org. Chem.2015,11, 2540–2548, doi:10.3762/bjoc.11.274
imaging, ion-pairreceptors, rotaxane synthesis, squaraine rotaxanes, and synthtavidin technology. The article concludes with a short perspective of likely future directions in biomedical supramolecular chemistry.
Keywords: fluorescence; ion-pairreceptors; membrane transport; molecular imaging; rotaxane
][21][22]. The latest discovery is a set of molecular ZnDPA probes that selectively target parasite infections in living subjects such as Leishmaniasis, a lethal disease that afflicts many millions of people around the world [23].
Ion-pairreceptors
Our early experience with membrane transport raised
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Graphical Abstract
Figure 1:
The author as a teenager in his school uniform, but on the nearby Myrtleford golf course.