Beilstein J. Org. Chem.2022,18, 1410–1415, doi:10.3762/bjoc.18.146
on LPS-induced nitric oxide production in RAW 264.7 macrophages.
Keywords: lignanderivatives; nitric oxide production inhibition; norlignans; Selaginella sinensis; Introduction
Selaginella is the only genus of Selaginellaceae. As a representative of the earliest and still-surviving vascular plant
investigated. As a result, three new lignanderivatives 1–3 together with three known lignan glycosides 4–6 (Figure 1) were isolated. Their isolation, structural elucidation and inhibitory effects on LPS-induced nitric oxide production are reported.
Results and Discussion
Sinensiol H (1) was isolated as a pale
lignanderivatives, sinensiols H–J (1–3) and three known compounds (4–6), were obtained from the whole plants of Selaginella sinensis. The absolute configuration of compound 1 was established by comparison of calculated and experimental ECD spectra. Compounds 2 and 3, which possess a 1,4-diphenylbutane
Beilstein J. Org. Chem.2021,17, 2329–2339, doi:10.3762/bjoc.17.151
in the isolation and characterization of 14 lignanderivatives including three new neolignan glycosides (1–3), four phenolic glycosides including a new compound (15), and a new cyanoglycoside (16) from the organic extracts. The structures of the new compounds were established by NMR analysis (1H and