Hot shape transformation: the role of PSar dehydration in stomatocyte morphogenesis

• Remi Peters,
• Levy A. Charleston,
• Karinan van Eck,
• Teun van Berlo and
• Daniela A. Wilson

Beilstein J. Org. Chem. 2025, 21, 47–54, doi:10.3762/bjoc.21.5

• , triggering the release of water molecules from the hydrophilic layer. Consequently, enhanced interactions between polysarcosine chains ensue, culminating in a more rigid and less permeable membrane structure at an optimum dehydration at 70 °C. This augmented membrane permeability facilitates the buildup of

Cyclodextrins permeabilize DPPC liposome membranes: a focus on cholesterol content, cyclodextrin type, and concentration

• Ghenwa Nasr,
• Hélène Greige-Gerges,
• Sophie Fourmentin,
• Abdelhamid Elaissari and
• Nathalie Khreich

Beilstein J. Org. Chem. 2023, 19, 1570–1579, doi:10.3762/bjoc.19.115

• avoids a burst release of the drug from the carrier resulting in an ameliorated controlled release [6][7]. Nevertheless, CDs are known to induce considerable damages in the membrane structure and composition. In fact, CDs can alter the biophysical properties of the membrane by increasing its fluidity and

Heterogeneous photocatalysis in flow chemical reactors

• Christopher G. Thomson,
• Ai-Lan Lee and
• Filipe Vilela

Beilstein J. Org. Chem. 2020, 16, 1495–1549, doi:10.3762/bjoc.16.125

From chemical metabolism to life: the origin of the genetic coding process

• Antoine Danchin

Beilstein J. Org. Chem. 2017, 13, 1119–1135, doi:10.3762/bjoc.13.111

• because adequate tuning of the corresponding rates of synthesis depends on the volume that will be occupied by the synthesised compounds. Remarkably, rather than in prokaryotes, this hurdle is much easier to solve in eukaryotes with their endoplasmic reticulum, which is a kind of membrane structure folded

Membrane properties of hydroxycholesterols related to the brain cholesterol metabolism

• Malte Hilsch,
• Ivan Haralampiev,
• Peter Müller,
• Daniel Huster and
• Holger A. Scheidt

Beilstein J. Org. Chem. 2017, 13, 720–727, doi:10.3762/bjoc.13.71

• influence on lipid chain order, membrane permeability and formation of lateral domains. Keywords: cholesterol; fluorescence; hydroxycholesterol; membrane structure; NMR; Introduction Cholesterol is a major component of mammalian cell membranes with various biological functions. It plays a key role in

Benzothiadiazole oligoene fatty acids: fluorescent dyes with large Stokes shifts

• Lukas J. Patalag and
• Daniel B. Werz

Beilstein J. Org. Chem. 2016, 12, 2739–2747, doi:10.3762/bjoc.12.270

• -dipyrromethene) [11][12], BOIMPY- (bis(borondifluoride)-8-imidazodipyrromethene) [13] and pyrene-labeled fatty acids [14]. Of course, all these alterations might also affect the membrane structure and its dynamics. While the NBD-fluorophore suffers from unsuitable polarity, a pyrene motif disrupts the unpolar

Smart molecules for imaging, sensing and health (SMITH)

• Bradley D. Smith

Beilstein J. Org. Chem. 2015, 11, 2540–2548, doi:10.3762/bjoc.11.274

• molecules to promote flip-flop of phospholipids across cell membranes, and thus alter the membrane structure and function. In particular, we discovered compounds that can scramble the transmembrane distribution of phosphatidylserine, a crucial signaling phospholipid. The synthetic scramblases make

Effects of RAMEA-complexed polyunsaturated fatty acids on the response of human dendritic cells to inflammatory signals

• Éva Rajnavölgyi,
• Renáta Laczik,
• Viktor Kun,
• Lajos Szente and
• Éva Fenyvesi

Beilstein J. Org. Chem. 2014, 10, 3152–3160, doi:10.3762/bjoc.10.332

• acids are not produced by mammals, although they are essential for hormone synthesis and maintenance of cell membrane structure and integrity. They have recently been shown to inhibit inflammatory reactions and also emerged as potential treatment options for inflammatory diseases, such as rheumatoid

• mediated through the GP120 receptor without interfering with the cell membrane structure. Keywords: cell membrane; cell surface markers; cyclodextrin; enzyme immunoassay; flow cytometry; monocyte-derived dendritic cells; proinflammatory cytokines; RAMEA; solubilization; Introduction The n−3

• solubilized by RAMEA provide with a new tool for optimizing the anti-inflammatory effects exerted on human moDC and mediated via the GPR120 receptor without interfering with the cell membrane structure. Experimental Fatty acids, cyclodextrins The fatty acids were purchased from Sigma-Aldrich. The randomly

Preparation and evaluation of cyclodextrin polypseudorotaxane with PEGylated liposome as a sustained release drug carrier

• Kayoko Hayashida,
• Taishi Higashi,
• Daichi Kono,
• Keiichi Motoyama,
• Koki Wada and
• Hidetoshi Arima

Beilstein J. Org. Chem. 2014, 10, 2756–2764, doi:10.3762/bjoc.10.292

• useful as sustained gene transfer carriers [26][27]. Liposomes (LPs) are microscopic phospholipid vesicles with a bilayered membrane structure and are used as a promising drug carrier [28]. When conventional LPs are administrated intravenously, they are coated with plasma proteins, which results in a

Encapsulation of biocides by cyclodextrins: toward synergistic effects against pathogens

• Véronique Nardello-Rataj and
• Loïc Leclercq

Beilstein J. Org. Chem. 2014, 10, 2603–2622, doi:10.3762/bjoc.10.273

An expedient synthesis of 5-n-alkylresorcinols and novel 5-n-alkylresorcinol haptens

• Kirsti Parikka and
• Kristiina Wähälä

Beilstein J. Org. Chem. 2009, 5, No. 22, doi:10.3762/bjoc.5.22

• biological effects including antimutagenic activity [3][4][5][6], antibacterial properties [7], inhibition of enzymes [8][9][10][11][12] and interaction with biological membranes by incorporation to the membrane structure [13][14]. Whole grain rye and wheat products, linked to a healthy diet, are the most