Natural resorcylic lactones derived from alternariol

• Joachim Podlech

Beilstein J. Org. Chem. 2024, 20, 2171–2207, doi:10.3762/bjoc.20.187

• has been investigated thoroughly on its biological activities, especially on its toxicity [6][12]. Its phytotoxicity has already been noted in the first reports; it induced chlorosis when injected to the leaves of tobacco plants [110]. It turned out to be cytotoxic against HeLa and lymphoma L5178Y

• again from A. alternata [138], from A. brassicae [262], and further A. spp. [215][263], from Ulocladium sp. [210], Colletotrichum capsica [264], Setosphaeria sp. [265], Phyllosticta capitalensis [266], and from Fusarium guttiforme [267]. Isoaltenuene showed some phytotoxicity on tomato leaves at 20 µg

Bipolenins K–N: New sesquiterpenoids from the fungal plant pathogen Bipolaris sorokiniana

• Chin-Soon Phan,
• Hang Li,
• Simon Kessler,
• Peter S. Solomon,
• Andrew M. Piggott and
• Yit-Heng Chooi

Beilstein J. Org. Chem. 2019, 15, 2020–2028, doi:10.3762/bjoc.15.198

• germination. The putative biosynthetic relationships between the isolated sesquiterpenoids were also explored. Keywords: Bipolaris sorokiniana; phytotoxicity; sesquiterpenes; terpenes; Introduction Fungi belonging to the genus Bipolaris (teleomorph: Cochliobolus) have been reported to produce a diverse

• strain BRIP10943 (CS10) [14] and their phytotoxicity. This led to the isolation of four new sativene-type sesquiterpenoid natural products along with seven related known analogues and one sesterterpenoid. Herein, the isolation, structure elucidation and phytotoxic activities of these compounds are

• aldehyde moiety in 7. Interestingly, an earlier study showed that 7 promoted the elongation of the shoots of rice seedlings [20]. Compound 12 was reported to have a broad spectrum of biological activities, including phytotoxicity on juvenile plant Bromus tectorum [21], syncytium formation inhibitory

Biosynthesis of α-pyrones

• Till F. Schäberle

Beilstein J. Org. Chem. 2016, 12, 571–588, doi:10.3762/bjoc.12.56

• isolated from Leptosphaeria maculans and named phomapyrone A, as well as from the mediterranean ascoglossan mollusc Ercolania funereal, described as cyercene [51]. Phomenin A displayed phytotoxicity at a concentration of 100 µg/mL. Chemical synthesis approaches enabled then to investigate many more α

Pyridinoacridine alkaloids of marine origin: NMR and MS spectral data, synthesis, biosynthesis and biological activity

• Louis P. Sandjo,
• Victor Kuete and
• Maique W. Biavatti

Beilstein J. Org. Chem. 2015, 11, 1667–1699, doi:10.3762/bjoc.11.183

• , terpenoids, phenolics, polysaccharides and alkaloids [4]. Various bioactivity functions such as anticancer [5][6][7], phytotoxicity [8][9][10][11], antioxidant [12][13][14][15][16], antimicrobial [17][18][19], analgesic [20][21], hypotensive [22], hypoglycemic [23], antiprotozoal [24] and plant protecting

Bidirectional cross metathesis and ring-closing metathesis/ring opening of a C₂-symmetric building block: a strategy for the synthesis of decanolide natural products

• Bernd Schmidt and
• Oliver Kunz

Beilstein J. Org. Chem. 2013, 9, 2544–2555, doi:10.3762/bjoc.9.289

• this contribution, we demonstrate that this combination can be advantageously used for the synthesis of decanolides. These natural products share a ten-membered lactone structure and are normally isolated from fungi. Diverse bioactivities have been reported, such as phytotoxicity, cytotoxicity