HFIP as a versatile solvent in resorcin[n]arene synthesis

• Hormoz Khosravi,
• Valeria Stevens and
• Raúl Hernández Sánchez

Beilstein J. Org. Chem. 2024, 20, 2469–2475, doi:10.3762/bjoc.20.211

• reported herein may impact the synthesis of other macrocyclic arene species, e.g., calix[n]arenes, calix[4]pyrroles, pillar[n]arenes, and cucurbit[n]urils [90][91][92]. Perspective Supramolecular chemistry is a mature field that has crossed boundaries into many other scientific areas. However, the work

Fabrication, characterization and adsorption properties of cucurbit[7]uril-functionalized polycaprolactone electrospun nanofibrous membranes

• Changzhong Chen,
• Fengbo Liu,
• Xiongzhi Zhang,
• Zhiyong Zhao and
• Simin Liu

Beilstein J. Org. Chem. 2019, 15, 992–999, doi:10.3762/bjoc.15.97

• engineering [6], energy storage [7], biosensors [8], catalysis [9], and environmental engineering [10]. Various supramolecular host molecules such as cyclodextrins (CDs), calix[n]arenes, and pillar[n]arenes can form host–guest inclusion complexes (ICs) with numerous compounds due to their unique cavity

• /nanoreactor and supramolecular polymers, etc. [25][27][28][29][30][31][32]. Unlike other hosts such as CDs, calix[n]arenes, or pillar[n]arenes, the fabrication of CB[n]-functionalized nanofibers by electrospinning is a challenging task due to the poor solubility of CB[n] in common solvents. To develop CB[n

Synthesis of a water-soluble 2,2′-biphen[4]arene and its efficient complexation and sensitive fluorescence enhancement towards palmatine and berberine

• Xiayang Huang,
• Xinghua Zhang,
• Tianxin Qian,
• Junwei Ma,
• Lei Cui and
• Chunju Li

Beilstein J. Org. Chem. 2018, 14, 2236–2241, doi:10.3762/bjoc.14.198

• , medicine, and environment. Cyclodextrins [1][2][3][4], cucurbiturils [5][6][7][8][9][10][11], and calixarenes [12][13][14][15][16][17][18][19][20] have been widely used in aqueous supramolecular chemistry. In the past ten years, the chemistry of pillar[n]arenes has developed very quickly because of their

Synthesis and post-functionalization of alternate-linked-meta-para-[2ⁿ.1ⁿ]thiacyclophanes

• Wout De Leger,
• Koen Adriaensen,
• Koen Robeyns,
• Luc Van Meervelt,
• Joice Thomas,
• Björn Meijers,
• Mario Smet and
• Wim Dehaen

Beilstein J. Org. Chem. 2018, 14, 2190–2197, doi:10.3762/bjoc.14.192

• homodithiacalix[4]arenes by dynamic covalent chemistry [12][13][14]. Functionalization of homothiacalix[4]arenes was made possible by changing the precursors before macrocyclization (Scheme 1) [12]. Recently, pillar[n]arenes have attracted much interest as new supramolecular receptors due to their pillar-shaped

An amphiphilic pseudo[1]catenane: neutral guest-induced clouding point change

• Tomoki Ogoshi,
• Tomohiro Akutsu and
• Tada-aki Yamagishi

Beilstein J. Org. Chem. 2018, 14, 1937–1943, doi:10.3762/bjoc.14.167

• aggregation of the hydrophobic alkyl chain rings, which induced insolubilization of the bicyclic compound in aqueous media at 20 °C and a decrease in its clouding point. Keywords: amphiphilic molecules; host–guest complexes; lower critical solution temperature; pillar[n]arenes; pseudo[1]catenane

• –guest chemistry [5][6][7]. The molecules consist of a non-ionic amphiphilic part containing tri(ethylene oxide) moieties, and a hydrophobic part consisting of a pillar[n]arene core (Figure 1a; 1, n = 5; 2, n = 6). Pillar[n]arenes, which were first reported by our group [11], were used as the macrocyclic

• component because of their high functionality and superior host–guest properties with neutral guests [12][13][14][15][16]. The amphiphilic pillar[n]arenes 1 and 2 exhibit clouding points at 41 and 42 °C, respectively [5][6]. The oligo(ethylene oxide) moieties are solvated with water molecules at room