Hot shape transformation: the role of PSar dehydration in stomatocyte morphogenesis

• Remi Peters,
• Levy A. Charleston,
• Karinan van Eck,
• Teun van Berlo and
• Daniela A. Wilson

Beilstein J. Org. Chem. 2025, 21, 47–54, doi:10.3762/bjoc.21.5

• across various applications. In this study, we present a comprehensive methodology for synthesizing, self-assembling, and transforming polysarcosine-poly(benzyl glutamate) block copolymers, resulting in the formation of bowl-shaped vesicles, disks, and stomatocytes. Under ambient conditions, the shape

• suggests that shape transformations triggered by saccharose are more effective at higher temperatures [38]. Conclusion Self-assembled vesicles crafted from polysarcosine-poly(benzyl glutamate) block copolymers exhibit distinct properties compared to conventional systems like PEG-PS or PEG-PDLLA, notably

• to induce enough osmotic pressure to induce shape transformation. The use of saccharose which has a higher dehydration temperature then PEG or PSar seems to be more effective for use at high temperatures. In summary, the distinctive properties of polysarcosine-poly(benzyl glutamate) block copolymers