Beilstein J. Org. Chem.2014,10, 2903–2911, doi:10.3762/bjoc.10.308
polysaccharides gellan gum and κ-carrageenan. This system showed good bioadhesive properties and effective control of fluconazole release.
Keywords: cyclodextrins; eye drops; fluconazole; hydroxypropyl-β-cyclodextrin; sulfobutylether-β-cyclodextrin; Introduction
Fungal keratitis is a serious disease that can
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Graphical Abstract
Figure 1:
Phase solubility diagrams for fluconazole obtained with β-cyclodextrin derivatives at 25 °C in wate...