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Search for "tenacibactin" in Full Text gives 1 result(s) in Beilstein Journal of Organic Chemistry.

Tenacibactins K–M, cytotoxic siderophores from a coral-associated gliding bacterium of the genus Tenacibaculum

  • Yasuhiro Igarashi,
  • Yiwei Ge,
  • Tao Zhou,
  • Amit Raj Sharma,
  • Enjuro Harunari,
  • Naoya Oku and
  • Agus Trianto

Beilstein J. Org. Chem. 2022, 18, 110–119, doi:10.3762/bjoc.18.12

Graphical Abstract
  • submicromolar to micromolar ranges. Their iron-chelating activity was comparable to deferoxamine mesylate. Keywords: desferrioxamine; marine obligate bacterium; MS/MS analysis; tenacibactin; Tenacibaculum; Introduction Marine organisms continue to be a prolific resource of new bioactive natural products that
  • Cholester Packed Column, 10 × 250 mm, Nacalai Tesque) using an isocratic elution with 50% MeCN in 0.1% HCO2H over 40 min at a flow rate of 4 mL/min, yielding tenacibactin K (1, 31.6 mg, tR 28.0 min), tenacibactin L (2, 2.8 mg, tR 22.0 min), and tenacibactin M (3, 18.2 mg, tR 34.4 min). Tenacibactin K (1
  • ): pale brown powder; UV (MeOH) λmax nm (log ε): 201 (4.82) nm; IR (ATR) νmax: 3305, 2916, 2849, 1613, 1538, 1466 cm−1; 1H and 13C NMR, Table 1; HR–ESITOFMS (m/z): [M − H]− calcd for C33H60N5O8, 654.4447; found, 654.4449; [M + Na]+ calcd for C33H61N5O8Na, 678.4412; found, 678.4412. Tenacibactin L (2
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Published 13 Jan 2022
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