Advances in Zr-mediated radical transformations and applications to total synthesis

• Hiroshige Ogawa and
• Hugh Nakamura

Beilstein J. Org. Chem. 2026, 22, 71–87, doi:10.3762/bjoc.22.3

• Yamaguchi published a review on radical reactions catalyzed by zirconium complexes [6]. Their review provides a comprehensive summary, particularly of photo-redox reactions involving zirconium catalysis. In the present review, we focus on three aspects: 1) Zr-mediated stoichiometric radical reactions 2) Zr

• and accelerating the whole process. Zr-mediated catalytic radical reactions In recent years, numerous chemical transformations employing photoredox catalysts in combination with catalytic amounts of zirconium complexes have been reported. In this section, representative examples of such reactions are

• a photosensitizer, together with compound 22 as a sacrificial reductant, in the dimerization of benzyl bromide (19). The desired dimerized product 20 was obtained in 40% yield. This study highlights the potential of zirconium complexes as a photoredox catalyst, pointing to promising opportunities

Pyridine C(sp²)–H bond functionalization under transition-metal and rare earth metal catalysis

• Haritha Sindhe,
• Malladi Mounika Reddy,
• Karthikeyan Rajkumar,
• Akshay Kamble,
• Amardeep Singh,
• Anand Kumar and
• Satyasheel Sharma

Beilstein J. Org. Chem. 2023, 19, 820–863, doi:10.3762/bjoc.19.62

• demonstrated that the reaction in the presence of cationic zirconium complexes derived from zirconium dibenzyl complexes bearing tridentate [ONO]-type amine-bridged bis(phenolato) ligands and [Ph3C][B(C6F5)4] (Scheme 5), gave rise to ortho-selective C–H alkylated pyridines 19 and 21. It was observed that the

Aluminacyclopentanes in the synthesis of 3-substituted phospholanes and α,ω-bisphospholanes

• Vladimir A. D’yakonov,
• Alevtina L. Makhamatkhanova,
• Rina A. Agliullina,
• Leisan K. Dilmukhametova,
• Tat’yana V. Tyumkina and
• Usein M. Dzhemilev

Beilstein J. Org. Chem. 2016, 12, 406–412, doi:10.3762/bjoc.12.43

• with molybdenum hexacarbonyl. The structure of the complexes was proved by multinuclear 1H, 13C, and 31P spectroscopy. Keywords: aluminacyclopentanes; Dzhemilev reaction; molybdenum complexes; phospholanes; zirconium complexes; Introduction A widely used approach for the synthesis of cyclic

Metal–ligand multiple bonds as frustrated Lewis pairs for C–H functionalization

• Matthew T. Whited

Beilstein J. Org. Chem. 2012, 8, 1554–1563, doi:10.3762/bjoc.8.177

• role, as one can envision a bimolecular pathway to acid–base adduct formation (Figure 2a). Such dimerization does occur in cases with insufficient steric encumbrance (e.g., the bis-μ-imido zirconium complexes of Bergman, Figure 2b) [25]. Thus, as for the main-group FLPs of Stephan and others