The cell-type specific uptake of polymer-coated or micelle-embedded QDs and SPIOs does not provoke an acute pro-inflammatory response in the liver

Scholarly Works

• Suh, M.; Park, J. Y.; Ko, G. B.; Kim, J. Y.; Hwang, D. W.; Rees, L.; Conway, G. E.; Doak, S. H.; Kang, H.; Lee, N.; Hyeon, T.; Lee, Y.-S.; Lee, D. S. Optimization of micelle-encapsulated extremely small sized iron oxide nanoparticles as a T1 contrast imaging agent: biodistribution and safety profile. Journal of nanobiotechnology 2024, 22, 419. doi:10.1186/s12951-024-02699-8
• Liebold, I.; Meyer, S.; Heine, M.; Kuhl, A.; Witt, J.; Eissing, L.; Fischer, A. W.; Koop, A. C.; Kluwe, J.; Wiesch, J. S. Z.; Wehmeyer, M.; Knippschild, U.; Scheja, L.; Heeren, J.; Bosurgi, L.; Worthmann, A. TREM2 Regulates the Removal of Apoptotic Cells and Inflammatory Processes during the Progression of NAFLD. Cells 2023, 12, 341. doi:10.3390/cells12030341
• Aram, E.; Moeni, M.; Abedizadeh, R.; Sabour, D.; Sadeghi-Abandansari, H.; Gardy, J.; Hassanpour, A. Smart and Multi-Functional Magnetic Nanoparticles for Cancer Treatment Applications: Clinical Challenges and Future Prospects. Nanomaterials (Basel, Switzerland) 2022, 12, 3567. doi:10.3390/nano12203567
• Ahmadpoor, F.; Masood, A.; Feliu, N.; Parak, W. J.; Shojaosadati, S. A. The Effect of Surface Coating of Iron Oxide Nanoparticles on Magnetic Resonance Imaging Relaxivity. Frontiers in Nanotechnology 2021, 3. doi:10.3389/fnano.2021.644734
• Carambia, A.; Gottwick, C.; Schwinge, D.; Stein, S.; Digigow, R.; Şeleci, M.; Mungalpara, D.; Heine, M.; Schuran, F. A.; Corban, C.; Lohse, A. W.; Schramm, C.; Heeren, J.; Herkel, J. Nanoparticle-mediated targeting of autoantigen peptide to cross-presenting liver sinusoidal endothelial cells protects from CD8 T-cell-driven autoimmune cholangitis. Immunology 2021, 162, 452–463. doi:10.1111/imm.13298
• Gutiérrez, L.; de la Cueva, L.; Moros, M.; Mazario, E.; de Bernardo, S.; de la Fuente, J. M.; Morales, M. P.; Salas, G. Aggregation effects on the magnetic properties of iron oxide colloids. Nanotechnology 2019, 30, 112001. doi:10.1088/1361-6528/aafbff
• Wu, T.; Liang, X.; He, K.; Wei, T.; Wang, Y.; Lu, J.; Yao, Y.; Zhang, T.; Xue, Y.; Tang, M. MPA-modified CdTe quantum dots increased interleukin-1beta secretion through MyD88-dependent Toll-like receptor pathway and NLRP3 inflammasome activation in microglia. Toxicology in vitro : an international journal published in association with BIBRA 2018, 52, 41–51. doi:10.1016/j.tiv.2018.05.014
• Wang, Y.; Tang, M. Review of in vitro toxicological research of quantum dot and potentially involved mechanisms. The Science of the total environment 2018, 625, 940–962. doi:10.1016/j.scitotenv.2017.12.334
• Reifarth, M.; Hoeppener, S.; Schubert, U. S. Uptake and Intracellular Fate of Engineered Nanoparticles in Mammalian Cells: Capabilities and Limitations of Transmission Electron Microscopy—Polymer‐Based Nanoparticles. Advanced materials (Deerfield Beach, Fla.) 2018, 30, 1703704. doi:10.1002/adma.201703704
• Liu, Y.; Workalemahu, B.; Jiang, X. The Effects of Physicochemical Properties of Nanomaterials on Their Cellular Uptake In Vitro and In Vivo. Small (Weinheim an der Bergstrasse, Germany) 2017, 13, 1701815. doi:10.1002/smll.201701815
• Parvani, J. G.; Jackson, M. W. Silencing the roadblocks to effective triple-negative breast cancer treatments by siRNA nanoparticles. Endocrine-related cancer 2017, 24, R81–R97. doi:10.1530/erc-16-0482
• Feliu, N.; Docter, D.; Heine, M.; del Pino, P.; Ashraf, S.; Kolosnjaj-Tabi, J.; Macchiarini, P.; Nielsen, P. E.; Alloyeau, D.; Gazeau, F.; Stauber, R. H.; Parak, W. J. In vivo degeneration and the fate of inorganic nanoparticles. Chemical Society reviews 2016, 45, 2440–2457. doi:10.1039/c5cs00699f
• Bargheer, D.; Giemsa, A.; Freund, B.; Heine, M.; Waurisch, C.; Stachowski, G. M.; Hickey, S. G.; Eychmüller, A.; Heeren, J.; Nielsen, P. The distribution and degradation of radiolabeled superparamagnetic iron oxide nanoparticles and quantum dots in mice. Beilstein journal of nanotechnology 2015, 6, 111–123. doi:10.3762/bjnano.6.11
• Bargheer, D.; Nielsen, J.; Gébel, G.; Heine, M.; Salmen, S. C.; Stauber, R.; Weller, H.; Heeren, J.; Nielsen, P. The fate of a designed protein corona on nanoparticles in vitro and in vivo. Beilstein journal of nanotechnology 2015, 6, 36–46. doi:10.3762/bjnano.6.5

Explore citations to this article at