False positives and false negatives measure less than 0.001% in labeling ssDNA with osmium tetroxide 2,2’-bipyridine

Anastassia Kanavarioti
Beilstein J. Nanotechnol. 2016, 7, 1434–1446. https://doi.org/10.3762/bjnano.7.135

Supporting Information

Supporting Information File 1: Additional figures are included to illustrate the stability of oligos with C(Me)(OsBp), T(OsBp) and U(OsBp) and the osmylation reaction of a 15-mer oligo monitored by IE HPLC.
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False positives and false negatives measure less than 0.001% in labeling ssDNA with osmium tetroxide 2,2’-bipyridine
Anastassia Kanavarioti
Beilstein J. Nanotechnol. 2016, 7, 1434–1446. https://doi.org/10.3762/bjnano.7.135

How to Cite

Kanavarioti, A. Beilstein J. Nanotechnol. 2016, 7, 1434–1446. doi:10.3762/bjnano.7.135

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Scholarly Works

  • Kanavarioti, A.; Rehman, M. H.; Qureshi, S.; Rafiq, A.; Sultan, M. High Sensitivity and Specificity Platform to Validate MicroRNA Biomarkers in Cancer and Human Diseases. Non-coding RNA 2024, 10, 42. doi:10.3390/ncrna10040042
  • Kanavarioti, A.; Rehman, M. H.; Qureshi, S.; Rafiq, A.; Sultan, M. Analytical platform to validate microRNA biomarkers for cancer or disease with practically 100% sensitivity and specificity. Cold Spring Harbor Laboratory 2024. doi:10.1101/2024.05.20.24307547
  • Kanavarioti, A. Femtomolar-level PCR-free quantification of microRNA cancer biomarkers in serum. Cold Spring Harbor Laboratory 2023. doi:10.1101/2022.12.30.522268
  • Kang, A. S. W.; Bernasconi, J. G.; Jack, W. E.; Kanavarioti, A. Ready-to-use nanopore platform for the detection of any DNA/RNA oligo at attomole range using an Osmium tagged complementary probe. Scientific reports 2020, 10, 19790. doi:10.1038/s41598-020-76667-1
  • Kang, A. S. W.; Bernasconi, J. G.; Jack, W. E.; Kanavarioti, A. Ready-to-use nanopore platform for the detection of any DNA/RNA oligo at attomole range using an Osmium tagged complementary probe. Cold Spring Harbor Laboratory 2020. doi:10.1101/2020.10.05.327460
  • Sultan, M.; Kanavarioti, A. Nanopore device-based fingerprinting of RNA oligos and microRNAs enhanced with an Osmium tag. Scientific reports 2019, 9, 14180. doi:10.1101/664169
  • Kanavarioti, A. HPLC methods for purity evaluation of man-made single-stranded RNAs. Scientific reports 2019, 9, 1019. doi:10.1038/s41598-018-37642-z

Patents

  • KANAVARIOTI ANASTASSIA. Osmium tagged probes for nucleic acid detection. US 11884968 B2, Jan 30, 2024.
  • KANAVARIOTI ANASTASSIA. Nanopore platform for DNA/RNA oligo detection using an osmium tagged complementary probe. US 11427859 B2, Aug 30, 2022.
  • KANAVARIOTI ANASTASSIA. Nanopore platform for DNA/RNA oligo detection using an osmium tagged complementary probe. US 11111527 B1, Sept 7, 2021.
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