Development of a mucoadhesive drug delivery system and its interaction with gastric cells

• Ahmet Baki Sahin,
• Serdar Karakurt and
• Deniz Sezlev Bilecen

Beilstein J. Nanotechnol. 2025, 16, 371–384, doi:10.3762/bjnano.16.28

• nanoparticles is a dynamic process where both endocytosis and exocytosis are involved. The uptake also depends on the concentration of nanoparticles and the duration of the process. Studies conducted with the AGS cell line revealed that nanoparticle internalization generally reaches a plateau within the first 2

• potential distributions The size of Alg and EudAlg nanoparticles were analyzed by dynamic light scattering (Malvern Zetasizer Nano-ZS) at 25 °C. The nanoparticles were suspended in ddH2O; for each sample, three measurements were performed, twelve runs each, to obtain the distributions. Disposable

Enhancing mechanical properties of chitosan/PVA electrospun nanofibers: a comprehensive review

• Nur Areisman Mohd Salleh,
• Amalina Muhammad Afifi,
• Fathiah Mohamed Zuki and
• Hanna Sofia SalehHudin

Beilstein J. Nanotechnol. 2025, 16, 286–307, doi:10.3762/bjnano.16.22

• Viscoelasticity is another property relevant to nanofibers, which combines both elastic and viscous responses to deformation. Viscoelastic properties, including storage modulus and loss modulus, can be tested using dynamic mechanical analysis (DMA) or dynamic mechanical thermal analysis (DMTA). This technique

• as the additional parameter [140]. The presence of chitosan in PVA membranes is expected to increase the storage modulus because of the higher stiffness of chitosan chains compared to PVA chains, as reported from DMA tests by Parparita and coworkers [141]. Koosha et al. [59] measured the dynamic

• bonds, such as hydrogen bonds, ionic interactions, coordinate bonds, and dynamic covalent bonds [175]. These bonds are generally weaker than chemical cross-links and can break under deformation. However, physical cross-linking is considered more environmentally friendly compared to chemical cross

Preferential enrichment and extraction of laser-synthesized nanoparticles in organic phases

• Theo Fromme,
• Maximilian L. Spiekermann,
• Florian Lehmann,
• Stephan Barcikowski,
• Thomas Seidensticker and
• Sven Reichenberger

Beilstein J. Nanotechnol. 2025, 16, 254–263, doi:10.3762/bjnano.16.20

• to the two simultaneously occurring and commonly accepted nanoparticle formation mechanisms happening during the plume phase of LAL (picosecond to longer nanosecond time scale) [57][58]. Recent spatiotemporal, large-scale molecular dynamic simulations show that the thermal history of nanoparticles

Radiosensitizing properties of dual-functionalized carbon nanostructures loaded with temozolomide

• Radmila Milenkovska,
• Nikola Geskovski,
• Dushko Shalabalija,
• Ljubica Mihailova,
• Petre Makreski,
• Dushko Lukarski,
• Igor Stojkovski,
• Maja Simonoska Crcarevska and
• Kristina Mladenovska

Beilstein J. Nanotechnol. 2025, 16, 229–251, doi:10.3762/bjnano.16.18

• effects on the proliferation of cancer cells by blocking the cell cycle in the G0/G1 phase and increasing the osmotic pressure [91][92]. In addition, in a paper of Xu et al. [93], dynamic biological interactions between PEG and cells on the molecular level were clarified, explaining both the inhibitory

A review of metal-organic frameworks and polymers in mixed matrix membranes for CO₂ capture

• Charlotte Skjold Qvist Christensen,
• Nicholas Hansen,
• Mahboubeh Motadayen,
• Nina Lock,
• Martin Lahn Henriksen and
• Jonathan Quinson

Beilstein J. Nanotechnol. 2025, 16, 155–186, doi:10.3762/bjnano.16.14

• flexibility, which may undergo dynamic changes in response to external stimuli, such as pressure and temperature. This characteristic allows for gated CO2 adsorption under specific conditions [44], which presents itself as a unique strategy to selectively control CO2 separation in gas mixtures. For instance

Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy

• Naths Grazia Sukubo,
• Paolo Bigini and
• Annalisa Morelli

Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10

• characteristics [13][14]. This dynamic and complex spectrum of macrophage activity features nuanced challenges and opportunities in leveraging macrophage responses to enhance the therapeutic potential of NCs. Recent research has highlighted the dual role of macrophages in the context of nanomedicine. While their

• therapeutic effects remains a significant challenge, as their activation states are dynamic and often characterized by mixed or transitional phenotypes. This underscores the need for refined approaches to enhance efficacy while minimizing risks such as excessive immune activation. RNA-based therapeutics offer

Instance maps as an organising concept for complex experimental workflows as demonstrated for (nano)material safety research

• Benjamin Punz,
• Maja Brajnik,
• Joh Dokler,
• Jaleesia D. Amos,
• Litty Johnson,
• Katie Reilly,
• Anastasios G. Papadiamantis,
• Amaia Green Etxabe,
• Lee Walker,
• Diego S. T. Martinez,
• Steffi Friedrichs,
• Klaus M. Weltring,
• Nazende Günday-Türeli,
• Claus Svendsen,
• Christine Ogilvie Hendren,
• Mark R. Wiesner,
• Martin Himly,
• Iseult Lynch and
• Thomas E. Exner

Beilstein J. Nanotechnol. 2025, 16, 57–77, doi:10.3762/bjnano.16.7

• focused on silica (SiO2) nanomaterials in the size range of 50–100 nm (depending on the method used, i.e., transmission electron microscopy, nanoparticle tracking analysis, or dynamic light scattering (intensity or number distribution)) with different surface modifications, which are reported to be

A nanocarrier containing carboxylic and histamine groups with dual action: acetylcholine hydrolysis and antidote atropine delivery

• Elina E. Mansurova,
• Andrey A. Maslennikov,
• Anna P. Lyubina,
• Alexandra D. Voloshina,
• Irek R. Nizameev,
• Marsil K. Kadirov,
• Anzhela A. Mikhailova,
• Polina V. Mikshina,
• Albina Y. Ziganshina and
• Igor S. Antipin

Beilstein J. Nanotechnol. 2025, 16, 11–24, doi:10.3762/bjnano.16.2

• weighed on a Sartorius CP2P microbalance (Germany) in tin capsules. Quantitative measurements and data analysis were performed with Callidus 4.1 software. Hydrodynamic size and molecular weight were analyzed with a ZetaSizer Nano dynamic light scattering photon correlation spectrometer from Malvern, UK

Mechanistic insights into endosomal escape by sodium oleate-modified liposomes

• Ebrahim Sadaqa,
• Satrialdi,
• Fransiska Kurniawan and
• Diky Mudhakir

Beilstein J. Nanotechnol. 2024, 15, 1667–1685, doi:10.3762/bjnano.15.131

• enable the exploration of complex lipid–membrane interactions and dynamic molecular processes at an atomistic level, offering unparalleled insights into mechanisms that are challenging to observe experimentally. By capturing processes such as membrane destabilization, pore formation, and lipid fusion, MD

• , stabilizing at higher values, indicative of its dynamic integration into the bilayer. In contrast, AUR maintains lower RMSD values, suggesting a more controlled and stable interaction with the membrane. This difference in RMSD profiles further emphasizes the distinct interaction dynamics of OLA and AUR with

• higher level of hydrogen bonding indicates strong interactions with the lipid headgroups, stabilizing AUR at the membrane surface. The temporal fluctuations in the number of hydrogen bonds suggest dynamic interactions, with periodic increases possibly reflecting reorientation events or transient binding

Heterogeneous reactions in a HFCVD reactor: simulation using a 2D model

• Xochitl Aleyda Morán Martínez,
• José Alberto Luna López,
• Zaira Jocelyn Hernández Simón,
• Gabriel Omar Mendoza Conde,
• José Álvaro David Hernández de Luz and
• Godofredo García Salgado

Beilstein J. Nanotechnol. 2024, 15, 1627–1638, doi:10.3762/bjnano.15.128

• ), (∇u)T is the transposed velocity gradient tensor, τ is the viscous stress tensor (Pa), μ is the dynamic viscosity (Pa·s), Q includes heat sources other than viscous dissipation (W·m−3), and δij is the Kronecker delta symbol. All equations in this section were taken from [26], except Equation 5, which

The round-robin approach applied to nanoinformatics: consensus prediction of nanomaterials zeta potential

• Dimitra-Danai Varsou,
• Arkaprava Banerjee,
• Joyita Roy,
• Kunal Roy,
• Giannis Savvas,
• Haralambos Sarimveis,
• Ewelina Wyrzykowska,
• Mateusz Balicki,
• Tomasz Puzyn,
• Georgia Melagraki,
• Iseult Lynch and
• Antreas Afantitis

Beilstein J. Nanotechnol. 2024, 15, 1536–1553, doi:10.3762/bjnano.15.121

• [36], the following four were included in this study because of the completeness of the data (absence of data gaps): the NMs’ core chemistry, coating, morphology, and hydrodynamic diameter measured using dynamic light scattering (DLS). The ZP of the NMs was measured in water (pH 6.5–8.5). To enrich

Electrochemical nanostructured CuBTC/FeBTC MOF composite sensor for enrofloxacin detection

• Thi Kim Ngan Nguyen,
• Tien Dat Doan,
• Huy Hieu Luu,
• Hoang Anh Nguyen,
• Thi Thu Ha Vu,
• Quang Hai Tran,
• Ha Tran Nguyen,
• Thanh Binh Dang,
• Thi Hai Yen Pham and
• Mai Ha Hoang

Beilstein J. Nanotechnol. 2024, 15, 1522–1535, doi:10.3762/bjnano.15.120

• significantly enhanced the electrochemical response of ENR, increasing the signal by more than ten times compared to the unmodified electrode. Under optimal analytical conditions, the sensor exhibited three dynamic ranges for ENR detection, that is, 0.005 to 0.100 µM, 0.1 to 1.0 µM, and 1 to 13 µM, with

• adsorptive stripping square wave voltammetry. The sensor fabricated with an optimal weight ratio between CuBTC and FeBTC (5:5) exhibited the highest signal for enrofloxacin detection. Notably, the sensor showed excellent performance with good reproducibility (RSD = 3.83%), a large dynamic range from 0.05 to

Integrating high-performance computing, machine learning, data management workflows, and infrastructures for multiscale simulations and nanomaterials technologies

• Fabio Le Piane,
• Mario Vozza,
• Matteo Baldoni and
• Francesco Mercuri

Beilstein J. Nanotechnol. 2024, 15, 1498–1521, doi:10.3762/bjnano.15.119

• has emerged as a pivotal catalyst, revolutionizing the infrastructures for data [28]. Cloud technologies represent the most efficient and dynamic means to facilitate the seamless sharing of knowledge across diverse platforms. The inherent scalability, flexibility, and accessibility of cloud-based

• . This integration fosters a seamless transition from theoretical concepts to practical workflows. Researchers can articulate their thought processes, present results visually, and iterate on their code, fostering a dynamic and iterative research environment. Moreover, thanks to the different media we

Lithium niobate on insulator: an emerging nanophotonic crystal for optimized light control

• Midhun Murali,
• Amit Banerjee and
• Tanmoy Basu

Beilstein J. Nanotechnol. 2024, 15, 1415–1426, doi:10.3762/bjnano.15.114

• effect (largest electro-optic coefficient r33 = 27 pm/V at 1500 nm) [13], enables dynamic control of the reflection spectrum of DBR through applied electric fields, unlocking functionalities such as wavelength filtering and modulation [9][11][12]. LiNbO3 is transparent across a broad spectrum, spanning

• proposed LN-based PhCs can be easily integrated with other electro-optic devices, enabling dynamic tuning of the photonic bandgap through an applied electric field. This could be useful for creating tunable filters or modulators for high-power applications. However, successful implementation relies on

Nanotechnological approaches for efficient N2B delivery: from small-molecule drugs to biopharmaceuticals

• Selin Akpinar Adscheid,
• Akif E. Türeli,
• Nazende Günday-Türeli and
• Marc Schneider

Beilstein J. Nanotechnol. 2024, 15, 1400–1414, doi:10.3762/bjnano.15.113

• considered a challenge because of the existence of the blood–brain barrier (BBB, Figure 1), which is composed of several cell types [7]. The BBB is a dynamic and selective interface between the systemic circulation and the brain [8]. The structure of the healthy BBB relies on the endothelial cells and the

A biomimetic approach towards a universal slippery liquid infused surface coating

• Ryan A. Faase,
• Madeleine H. Hummel,
• AnneMarie V. Hasbrook,
• Andrew P. Carpenter and
• Joe E. Baio

Beilstein J. Nanotechnol. 2024, 15, 1376–1389, doi:10.3762/bjnano.15.111

• BSA [36]. Similar surface-induced thrombus properties were observed in other SLIPS applications, where, in comparison to untreated surfaces, SLIPS-treated surfaces under dynamic blood flow yielded significantly lower thrombi weights [4]. Finally, platelet adhesion was quantified from SEM micrographs

Hymenoptera and biomimetic surfaces: insights and innovations

• Vinicius Marques Lopez,
• Carlo Polidori and
• Rhainer Guillermo Ferreira

Beilstein J. Nanotechnol. 2024, 15, 1333–1352, doi:10.3762/bjnano.15.107

• ligustica) facilitate nectar-dipping by minimizing drag, enabling the bees to feed more efficiently [75]. The unique morphology and dynamic movement of the bee’s hairy tongue optimizes nectar feeding while conserving energy, providing insights into design methodologies for fluid transport devices using

• significant potential for biomimetic applications, particularly within aerospace engineering. For instance, the segmented and flexible structure of a bee’s metasoma facilitates efficient and dynamic flight maneuvers [184]. Bees optimize their aerodynamic performance and maneuverability through biomorphic

Nanoarchitectonics with cetrimonium bromide on metal nanoparticles for linker-free detection of toxic metal ions and catalytic degradation of 4-nitrophenol

• Akash Kumar and
• Raja Gopal Rayavarapu

Beilstein J. Nanotechnol. 2024, 15, 1312–1332, doi:10.3762/bjnano.15.106

• nanostructures were measured using an Epoch2 spectrophotometer (BioTek, USA). Hydrodynamic radius and polydispersity index (PDI) were measured using dynamic light scattering (Zetasizer Nano ZS, Malvern, UK). The zeta potential measurements were conducted to determine the surface charge for both isotropic and

Interaction of graphene oxide with tannic acid: computational modeling and toxicity mitigation in C. elegans

• Romana Petry,
• James M. de Almeida,
• Francine Côa,
• Felipe Crasto de Lima,
• Diego Stéfani T. Martinez and
• Adalberto Fazzio

Beilstein J. Nanotechnol. 2024, 15, 1297–1311, doi:10.3762/bjnano.15.105

• sheets. TA did not improve the stability of these samples. After the 24 h, only the suspensions of 1 mg·L−1 of GO did not exhibit visual precipitation (Supporting Information File 1, Figure S1a). The results of dynamic light scattering (DLS) measurements presented in Table S1 (Supporting Information File

• added, and the suspension was sonicated in an ultrasonic bath. The sonication time was controlled by analyzing the material’s hydrodynamic diameters by dynamic light scattering (DLS). Dispersion aliquots for measurement were collected every 10 min, and the sonication was performed until there were no

Dual-functionalized architecture enables stable and tumor cell-specific SiO₂NPs in complex biological fluids

• Iris Renata Sousa Ribeiro,
• Raquel Frenedoso da Silva,
• Romênia Ramos Domingues,
• Adriana Franco Paes Leme and
• Mateus Borba Cardoso

Beilstein J. Nanotechnol. 2024, 15, 1238–1252, doi:10.3762/bjnano.15.100

• 1.0 mg·mL–1) and later used for the quantification of captured SiO2NPs-ZW-FO. The calculations were performed using the value obtained at the maximum of the emission band. Stability of SiO2NPs in cell culture medium and human plasma Dynamic light scattering (DLS) measurements were performed to

• ions. The 20 most intense peptide ions with charge state ≥2 were sequentially isolated to a target value of 5000 and fragmented by collision-induced dissociation in the linear ion trap using a normalized collision energy of 35%. Dynamic exclusion was enabled with an exclusion size list of 500 peptides

• increase in the hydrodynamic diameter for the SiO2NPs-ZW-FO may be associated with their subtle aggregation after the addition of folate or simply by the change in the dynamic structure of the particle since folate is hydrophobic [35] and can alter the arrangement of water molecules around the NP. Zeta

Enhanced catalytic reduction through in situ synthesized gold nanoparticles embedded in glucosamine/alginate nanocomposites

• Chi-Hien Dang,
• Le-Kim-Thuy Nguyen,
• Minh-Trong Tran,
• Van-Dung Le,
• Nguyen Minh Ty,
• T. Ngoc Han Pham,
• Hieu Vu-Quang,
• Tran Thi Kim Chi,
• Tran Thi Huong Giang,
• Nguyen Thi Thanh Tu and
• Thanh-Danh Nguyen

Beilstein J. Nanotechnol. 2024, 15, 1227–1237, doi:10.3762/bjnano.15.99

• microscopy (TEM) and selected area electron diffraction (SAED) were carried out using a JEOL JEM-2100 instrument. Crystal structure characterizations of AuNPs were carried out via XRD diffraction. Zeta potential and dynamic light scattering (DLS) measurements were carried out on gel solutions (1.0 mg·mL−1

Quantum-to-classical modeling of monolayer Ge₂Se₂ and its application in photovoltaic devices

• Anup Shrivastava,
• Shivani Saini,
• Dolly Kumari,
• Sanjai Singh and
• Jost Adam

Beilstein J. Nanotechnol. 2024, 15, 1153–1169, doi:10.3762/bjnano.15.94

• the investigated structure’s dynamic stability. Electronic and transport properties The electronic properties of materials play a crucial role in predicting the material behavior and transport parameters and, hence, its prospective applications. We investigated the electronic properties of monolayer

Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis

• Damai Ria Setyawati,
• Fransiska Christydira Sekaringtyas,
• Riyona Desvy Pratiwi,
• A’liyatur Rosyidah,
• Rohimmahtunnissa Azhar,
• Nunik Gustini,
• Gita Syahputra,
• Idah Rosidah,
• Etik Mardliyati,
• Tarwadi and
• Sjaikhurrizal El Muttaqien

Beilstein J. Nanotechnol. 2024, 15, 1105–1116, doi:10.3762/bjnano.15.89

• dynamic endothelial fenestrations to reach HSCs in the perisinusoidal space or even hepatocytes [24][29]. Smaller nanocarriers (10–20 nm) can be taken up rapidly by hepatocytes [32]. Besides the size of the administered nanocarriers, surface properties also play an important role in dictating

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

• Shakhzodjon Uzokboev,
• Khojimukhammad Akhmadbekov,
• Ra’no Nuritdinova,
• Salah M. Tawfik and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

• [61]. Nanoparticle size: The nanoparticle size can be determined using a variety of methods including dynamic (DLS) and static (SLS) light scattering; TEM, SEM, and AFM are also widely employed [62][63]. DLS and SLS can detect particle size by determining changes in distribution of particle size

• a linear dynamic range of 0 to 1250 μM, with a LOD of 14 μM. Based on the selective enzymatic release of H2O2, the developed solid kit could be used to detect many biomarkers, including glucose, lactate, uric acid, and cholesterol [118]. Humidity sensing: One area that has shown promise in the field

Signal generation in dynamic interferometric displacement detection

• Knarik Khachatryan,
• Simon Anter,
• Michael Reichling and
• Alexander von Schmidsfeld

Beilstein J. Nanotechnol. 2024, 15, 1070–1076, doi:10.3762/bjnano.15.87