Bioselectivity of silk protein-based materials and their bio-inspired applications

• Hendrik Bargel,
• Vanessa T. Trossmann,
• Christoph Sommer and
• Thomas Scheibel

Beilstein J. Nanotechnol. 2022, 13, 902–921, doi:10.3762/bjnano.13.81

• biomedicine and tissue engineering, since they exhibit promising chemical and physical properties, such as bioactivity, structural integrity, and cell stimulation [29][30]. Biomimetic materials modulating specific cellular responses and tissue regeneration have been developed by adjusting and modifying

• of proteins, microbes, and cells should be guided by material-related surface properties to create bioinert, bioactive, or biomimetic biomaterials. 1.3 Antiadhesive and anti-fouling protein surfaces Nature has evolved a diverse portfolio of anti-adhesive, antimicrobial and antifouling methods

• and antifouling surfaces have been successfully generated by soft photolithography, micro-molding or nanopatterning techniques [57]. Moreover, the biomimetic application Sharklet® textured similarly to shark skin has not only been reported to be antiadhesive against green algae spores and bacterial

Micro-structures, nanomechanical properties and flight performance of three beetles with different folding ratios

• Jiyu Sun,
• Pengpeng Li,
• Yongwei Yan,
• Fa Song,
• Nuo Xu and
• Zhijun Zhang

Beilstein J. Nanotechnol. 2022, 13, 845–856, doi:10.3762/bjnano.13.75

• insects in flight and to imitate the flight of insects [14][15]. Insect wings play a major role here. Hence, examining their flight parameters is crucially important to design biomimetic FMAVs [16][17]. It is increasingly clear that most insects obtain useful force with the help of aerodynamic mechanisms

• have a critical effect on the flight performance and will be useful regarding the design of biomimetic MAVs. Wind tunnels are an effective tool to investigate flapping-wing flight and aerodynamic characteristics [29]. The wing tip trajectories of the hind wings of a beetle species (Protaetia

• the following, which will provide some reference for the design of biomimetic deployable FWMAVs. Materials and Methods Beetles Three beetle species with different folding ratios, Protaetia brevitarsis, Anoplophora chinensis, and Trypoxylus dichotomus, were selected for the experiments. The three adult

Temperature and chemical effects on the interfacial energy between a Ga–In–Sn eutectic liquid alloy and nanoscopic asperities

• Yujin Han,
• Pierre-Marie Thebault,
• Corentin Audes,
• Xuelin Wang,
• Haiwoong Park,
• Jian-Zhong Jiang and
• Arnaud Caron

Beilstein J. Nanotechnol. 2022, 13, 817–827, doi:10.3762/bjnano.13.72

• -temperature-liquid Ga-based alloys have been attracting interest from various scientific communities, including chemical [1], biomimetic [2], microfluidic [3], electrical [4], and materials science [5]. This increased interest is due to the low viscosity and high and electrical conductivity of these alloys

Hierachical epicuticular wax coverage on leaves of Deschampsia antarctica as a possible adaptation to severe environmental conditions

• Elena V. Gorb,
• Iryna A. Kozeretska and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2022, 13, 807–816, doi:10.3762/bjnano.13.71

• ., Asclepiadaceae and Cactaceae) [15], plays a crucial role in the protection from water loss. Biomimetic potential Since the discovery of the lotus effect [43], different properties of superhydrophobic surfaces in plants, which are highly relevant for modern technologies, such as self-cleaning, fluid drag

• reduction, or holding air layers at a surface, have been described and their biomimetic applications have been discussed. Phylogenetic trees indicate that superhydrophobicity evolved as a consequence of the conquest of land about 450 million years ago and may be a key innovation in the evolution of

Hierarchical Bi₂WO₆/TiO₂-nanotube composites derived from natural cellulose for visible-light photocatalytic treatment of pollutants

• Zehao Lin,
• Zhan Yang and
• Jianguo Huang

Beilstein J. Nanotechnol. 2022, 13, 745–762, doi:10.3762/bjnano.13.66

• photocatalytic reduction of Cr(VI), while hydroxyl radicals and reactive holes contributed to the photocatalytic degradation of rhodamine B. Keywords: biomimetic synthesis; cellulose; nanoarchitectonics; nanocomposite; nanotubes; photocatalysis; pollutants; Introduction The direct emission of untreated

• control is expected to offer a solution [28]. Based on biomimetic synthesis, the morphological control of functional materials is accomplished by combining chemical building blocks and natural substances with unique structures. Natural cellulose products (e.g., filter paper for quantitative analysis

Micro- and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis

• Zahra Nabizadeh,
• Mahmoud Nasrollahzadeh,
• Hamed Daemi,
• Mohamadreza Baghaban Eslaminejad,
• Ali Akbar Shabani,
• Mehdi Dadashpour,
• Majid Mirmohammadkhani and
• Davood Nasrabadi

Beilstein J. Nanotechnol. 2022, 13, 363–389, doi:10.3762/bjnano.13.31

• purposes is the subject of many studies [19] in which natural polymers, synthetic polymers, or their combination were used to provide a biomimetic microenvironment, which not only includes biological cues, but also provides the desired mechanical properties. The progress in materials science has revealed

• biomimetic nanocomposites to imitate pseudostratified features of the ECM to develop bioinspired scaffolds [47][48][49]. 3.1.2.1 Nanoparticles (NPs). In recent years, NPs have been increasingly used in regenerative medicine (Table 1) and other medical areas. NPs have been successfully developed for drug

• the controlled and sustained release of KGN [71]. 3.1.2.2 Nanofibers. Nanofibers are a versatile class of nanomaterials characterized by two nanoscale dimensions and a third larger dimension (below 1000 nm) [33][101]. Their biomimetic properties and simplicity of fabrication make nanofibers potential

Self-assembly of amino acids toward functional biomaterials

• Huan Ren,
• Lifang Wu,
• Lina Tan,
• Yanni Bao,
• Yuchen Ma,
• Yong Jin and
• Qianli Zou

Beilstein J. Nanotechnol. 2021, 12, 1140–1150, doi:10.3762/bjnano.12.85

• these nanostructures. Therefore, as a new strategy, amino acid self-assembly needs further research to explore the biomimetic and biomedical applications of micro- and nanomaterials. Schematic diagram of amino acid regulatory self-assembly (amino acid–drugs, amino acid–photosensitizers, amino acid–metal

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

• Sepand Tehrani Fateh,
• Lida Moradi,
• Elmira Kohan,
• Michael R. Hamblin and
• Amin Shiralizadeh Dezfuli

Beilstein J. Nanotechnol. 2021, 12, 808–862, doi:10.3762/bjnano.12.64

Recent progress in magnetic applications for micro- and nanorobots

• Ke Xu,
• Shuang Xu and
• Fanan Wei

Beilstein J. Nanotechnol. 2021, 12, 744–755, doi:10.3762/bjnano.12.58

• used in medical MNRs [26]. For example, based on the combination of copolymer brushes and superparamagnetic nanoparticles, a biomimetic nanoreactor was proposed. It contained a magnetic field-responsive catalytic system, namely magnetic field-responsive binary deoxyribozyme (MaBiDZ) [27]. Also, it

• , with which cancer cells and non-cancerous cells can be distinguished. Furthermore, a cell sensor that uses MaBiDz for rapid detection and imaging of target mRNA biomarkers of metastatic breast cancer has been realized. Its function shows that it is likely to be used as a biomimetic organelle MNR in the

Physical constraints lead to parallel evolution of micro- and nanostructures of animal adhesive pads: a review

• Thies H. Büscher and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2021, 12, 725–743, doi:10.3762/bjnano.12.57

• might be potentially interesting for engineers as a kind of optimal solution by nature, the biomimetic implications of the discussed results are briefly presented. Keywords: adhesion; attachment devices; biomechanics; convergence; friction; substrate compliance; Review Animal attachment systems

• relatively high separation, the contribution of viscous forces to the adhesion and friction are enhanced due to the presence of a thin fluid layer in the contact area [247]. Significance for biomimetic applications Several different approaches to mimic natural adhesive systems have already been published

• great approach for the advancement of biomimetic innovations. For example, further research on the material–function relationship of the attachment pads can be useful for technical applications of artificial attachment systems with either surface-specific use or to provide universal solutions for

The impact of molecular tumor profiling on the design strategies for targeting myeloid leukemia and EGFR/CD44-positive solid tumors

• Nikola Geskovski,
• Nadica Matevska-Geshkovska,
• Simona Dimchevska Sazdovska,
• Marija Glavas Dodov,
• Kristina Mladenovska and
• Katerina Goracinova

Beilstein J. Nanotechnol. 2021, 12, 375–401, doi:10.3762/bjnano.12.31

• itself proved to be non-toxic to healthy BALB/c mice. The co-delivery strategy has the potential to overcome therapy-induced niche-mediated leukemia resistance in AML. Dong et al. developed a biomimetic NDDS composed of a mesoporous silica nanoparticulate core loaded with daunorubicin and coated with

Key for crossing the BBB with nanoparticles: the rational design

• Sonia M. Lombardo,
• Marc Schneider,
• Akif E. Türeli and
• Nazende Günday Türeli

Beilstein J. Nanotechnol. 2020, 11, 866–883, doi:10.3762/bjnano.11.72

• protein corona forming around them, by investigating the particle–cell interactions or by looking for biomimetic solutions. Blood–brain barrier anatomy. Inspired by [5]. Brain delivery routes. A) Local delivery. Drugs can reach the brain by direct injection through the meninges. B) Intranasal delivery

Multilayer capsules made of weak polyelectrolytes: a review on the preparation, functionalization and applications in drug delivery

• Varsha Sharma and
• Anandhakumar Sundaramurthy

Beilstein J. Nanotechnol. 2020, 11, 508–532, doi:10.3762/bjnano.11.41

• [34]. Certain limitations such as low stability and low EE have been reported in organic and inorganic templates, respectively. Interestingly, the deposition of an additional silica layer through a biomimetic mineralization process onto a protamine/PSS microcapsule formed on a CaCO3 template improved

Nanoarchitectonics: bottom-up creation of functional materials and systems

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2020, 11, 450–452, doi:10.3762/bjnano.11.36

• spectroscopy [37], bio-nanocomposites with clay nanoarchitectures for electrochemical devices [38], a biomimetic nanofluidic diode with polymeric carbon nitride nanotubes [39], and a unique Janus-micromotor applied as a luminescence sensor for sensitive TNT detection [40]. The variety of nanoarchitectonics

Understanding nanoparticle flow with a new in vitro experimental and computational approach using hydrogel channels

• Armel Boutchuen,
• Dell Zimmerman,
• Abdollah Arabshahi,
• John Melnyczuk and
• Soubantika Palchoudhury

Beilstein J. Nanotechnol. 2020, 11, 296–309, doi:10.3762/bjnano.11.22

• scaffold materials for the 3D bioprinting of biomimetic structures [38][39]. Therefore, we chose pHEMA hydrogels to build straight cylindrical channels mimicking sections of human vasculature for our experimental investigation of NP flow. In addition, we aimed to synthesize the hydrogel flow channels via a

• new, facile, and cost-effective approach. Here, we report a combined experimental and computational technique to serve as an in vitro assessment of the flow of NPs using novel pHEMA hydrogel channels as the biomimetic flow path. The flow of NPs was experimentally investigated with different iron oxide

• diffusion and hydrodynamic forces for the flow of these aqueous NP dispersions and additional frictional forces in the NP flow path due to the soft and uneven surface of the hydrogel channels. This size-dependent flow behavior of aqueous NP solutions within soft biomimetic channels is a key finding in terms

Rational design of block copolymer self-assemblies in photodynamic therapy

• Maxime Demazeau,
• Laure Gibot,
• Anne-Françoise Mingotaud,
• Patricia Vicendo,
• Clément Roux and
• Barbara Lonetti

Beilstein J. Nanotechnol. 2020, 11, 180–212, doi:10.3762/bjnano.11.15

• ones such as polyesters or polyacrylates. A second part focuses on important parameters for their design and the improvement of their efficiency. Finally, particular attention has been paid to the question of nanocarrier internalization and interaction with membranes (both biomimetic and cellular), and

• second part. A third part will focus on the interactions between the vectors with the cell membrane, either in its native form or in biomimetic models. Finally, cellular entrance processes and intracellular targeting will also be described, showing possible intracellular targeting methods as well as the

Molecular architectonics of DNA for functional nanoarchitectures

• Debasis Ghosh,
• Lakshmi P. Datta and
• Thimmaiah Govindaraju

Beilstein J. Nanotechnol. 2020, 11, 124–140, doi:10.3762/bjnano.11.11

• nose for the selective detection of volatile organic components [65]. DNA tetrahedron nanostructures The structural analogy to virus particles makes DNA polyhedrons highly appealing architectures with biomimetic functional relevance. Among all polyhedrons, tetrahedrons are the simplest architectural

Nanostructured and oriented metal–organic framework films enabling extreme surface wetting properties

• Andre Mähringer,
• Julian M. Rotter and
• Dana D. Medina

Beilstein J. Nanotechnol. 2019, 10, 1994–2003, doi:10.3762/bjnano.10.196

• . Keywords: antifog; antifouling; biomimetic coatings; metal–organic frameworks (MOFs); superhydrophilic; superoleophobic; thin films; vapor-assisted conversion; Introduction Over millions of years, plants and animals have evolved a spectrum of surface designs enabling specific wetting properties tailored

Nanoarchitectonics meets cell surface engineering: shape recognition of human cells by halloysite-doped silica cell imprints

• Elvira Rozhina,
• Ilnur Ishmukhametov,
• Svetlana Batasheva,
• Farida Akhatova and
• Rawil Fakhrullin

Beilstein J. Nanotechnol. 2019, 10, 1818–1825, doi:10.3762/bjnano.10.176

• -assembly of miniature building blocks to form biomimetic soft or rigid shells to encapsulate live cells rendering them with additional functionalities [7]. In general, there are three principal routes to engineer the cell walls or membranes of live cells: 1) deposition of charged or neutral polymers (that

Chiral nanostructures self-assembled from nitrocinnamic amide amphiphiles: substituent and solvent effects

• Hejin Jiang,
• Huahua Fan,
• Yuqian Jiang,
• Li Zhang and
• Minghua Liu

Beilstein J. Nanotechnol. 2019, 10, 1608–1617, doi:10.3762/bjnano.10.156

• chiral self-assembly gained from various noncovalent interactions is a very good biomimetic system due to the intrinsic dynamic nature of such materials and smart response to external stimuli. There are some works on the dynamic helical inversion in self-assembled structures triggered by the change of pH

A biomimetic nanofluidic diode based on surface-modified polymeric carbon nitride nanotubes

• Kai Xiao,
• Baris Kumru,
• Lu Chen,
• Lei Jiang,
• Bernhard V. K. J. Schmidt and
• Markus Antonietti

Beilstein J. Nanotechnol. 2019, 10, 1316–1323, doi:10.3762/bjnano.10.130

Biomimetic synthesis of Ag-coated glasswing butterfly arrays as ultra-sensitive SERS substrates for efficient trace detection of pesticides

• Guochao Shi,
• Mingli Wang,
• Yanying Zhu,
• Yuhong Wang,
• Xiaoya Yan,
• Xin Sun,
• Haijun Xu and
• Wanli Ma

Beilstein J. Nanotechnol. 2019, 10, 578–588, doi:10.3762/bjnano.10.59

• . China Faculty of science, Beijing University of Chemical Technology, Beijing 100029, P.R. China Department of Mathematics, NC State University, Raleigh, NC 276968205, USA 10.3762/bjnano.10.59 Abstract In this work, we report a biomimetic synthesis route of 3D Ag nanofilm/glasswing butterfly wing

• . However, these chemical methods cannot avoid aggregation phenomena, which is a major drawback. Recent years have witnessed a very high level of research interest in well-defined biomimetic compounds. Because the micro/nanomaterials in nature usually possess intrinsic hydrophobicity and high adhesion

• 3D biomimetic SERS substrate with a high density of “hot spots” was formed on a template of cicada wings via a simple one-step and reagent-free direct-current ion sputtering techniques by Prof. Han’s group [26]. These 3D plasmonic nanostructures are adopted because these 3D substrates offer a great

Biological and biomimetic surfaces: adhesion, friction and wetting phenomena

• Stanislav N. Gorb,
• Kerstin Koch and
• Lars Heepe

Beilstein J. Nanotechnol. 2019, 10, 481–482, doi:10.3762/bjnano.10.48

Ultraviolet patterns of flowers revealed in polymer replica – caused by surface architecture

• Anna J. Schulte,
• Matthias Mail,
• Lisa A. Hahn and
• Wilhelm Barthlott

Beilstein J. Nanotechnol. 2019, 10, 459–466, doi:10.3762/bjnano.10.45

• structure and its reflective properties is also relevant for biomimetic applications, for example, in the field of photovoltaics. Based on previous work, we selected three model species with distinct UV-patterns to explore the possible contribution of the surface architecture to the UV-signaling. Using a

• differences even within just the three model plants. From a technical point of view, these results are promising and important for different types of applications given that the optical properties of surfaces are becoming more relevant, for example, for hierarchically structured solar panels, biomimetic

Pull-off and friction forces of micropatterned elastomers on soft substrates: the effects of pattern length scale and stiffness

• Peter van Assenbergh,
• Marike Fokker,
• Julian Langowski,
• Jan van Esch,
• Marleen Kamperman and
• Dimitra Dodou

Beilstein J. Nanotechnol. 2019, 10, 79–94, doi:10.3762/bjnano.10.8

• performance of these biomimetic micropatterned adhesives is usually tested on hard substrates. Much less is known about the effect of geometry, feature size, and material properties on the performance of micropatterned adhesives when the substrate is deformable. Here, micropatterned adhesives of two stiffness

• substrate between the dimples. Keywords: adhesion; biomimetic micropatterned adhesive; colloidal lithography; friction; pull-off; soft substrate; Introduction Pull-off and friction forces of micropatterned adhesives as a function of geometry, feature size, and stiffness Over the last few decades

• , researchers have been developing micropatterned adhesives mimicking the geometry and material properties of biological dry adhesives [1][2][3][4][5]. Pull-off and friction forces of these biomimetic adhesives rely on the formation of intimate contact with the substrates [6], enabling physical interactions