Cytotoxic and proinflammatory effects of PVP-coated silver nanoparticles after intratracheal instillation in rats

• Nadine Haberl,
• Stephanie Hirn,
• Alexander Wenk,
• Jörg Diendorf,
• Matthias Epple,
• Blair D. Johnston,
• Fritz Krombach,
• Wolfgang G. Kreyling and
• Carsten Schleh

Beilstein J. Nanotechnol. 2013, 4, 933–940, doi:10.3762/bjnano.4.105

• most promising nanomaterials, and their usage in medical applications and consumer products is growing rapidly. To evaluate possible adverse health effects, especially to the lungs, the current study focused on the cytotoxic and proinflammatory effects of AgNP after the intratracheal instillation in

• consumer products is growing rapidly [1]. The antimicrobial properties of AgNP render them useful as a component in wound dressings or as coatings for catheters [2][3][4][5]. In addition, they are used in deodorants or applied in textiles as a protection against odor [6][7]. With regard to the use in

• after the instillation of 250 µg PVP-AgNP (Figure 8). Discussion According to the Woodrow–Wilson-Center database of nanotechnology-based products [28], silver is one of the most frequently used nanomaterials for consumer products. Due to the use of AgNP as aerosols in healthcare and hygiene spray

Characterization of protein adsorption onto FePt nanoparticles using dual-focus fluorescence correlation spectroscopy

• Pauline Maffre,
• Karin Nienhaus,
• Faheem Amin,
• Wolfgang J. Parak and
• G. Ulrich Nienhaus

Beilstein J. Nanotechnol. 2011, 2, 374–383, doi:10.3762/bjnano.2.43

• well-controlled physicochemical properties including size, shape, charge, chemical composition and solubility. Many of these NPs have already found their way into consumer products. Owing to their small size, NPs may potentially invade all parts of the human body including tissues, cells and even