Fabrication of hybrid nanocomposite scaffolds by incorporating ligand-free hydroxyapatite nanoparticles into biodegradable polymer scaffolds and release studies

• Balazs Farkas,
• Marina Rodio,
• Ilaria Romano,
• Alberto Diaspro,
• Romuald Intartaglia and
• Szabolcs Beke

Beilstein J. Nanotechnol. 2015, 6, 2217–2223, doi:10.3762/bjnano.6.227

• similarity to the mineral constituent of human bones, are bioactive and can be fairly easily bioconjugated [1]. HA NPs can enhance cell proliferation in bone tissue regeneration [2]. Tissue engineering is an interdisciplinary field that combines the principles of life sciences and engineering to improve

• tissue growth and functions. Whenever the need arises for a certain type of scaffold to be produced, all these fields have to be utilized together to get an appropriate solution. HA is an essential ingredient of normal bone and teeth and is widely used for bone tissue regeneration. Given the high degree

Oxygen-plasma-modified biomimetic nanofibrous scaffolds for enhanced compatibility of cardiovascular implants

• Anna Maria Pappa,
• Varvara Karagkiozaki,
• Silke Krol,
• Spyros Kassavetis,
• Dimitris Konstantinou,
• Charalampos Pitsalidis,
• Lazaros Tzounis,
• Nikos Pliatsikas and
• Stergios Logothetidis

Beilstein J. Nanotechnol. 2015, 6, 254–262, doi:10.3762/bjnano.6.24

• complications of thrombosis and implant failure. Thus, we herein fabricated poly-ε-caprolactone (PCL) electrospun nanofibrous scaffolds, to serve as coatings for cardiovascular implants and guide tissue regeneration. Oxygen plasma treatment was applied in order to modify the surface chemistry of the scaffold

• properties along with the topographical nanoscale features of the scaffolds could be very useful in the design of novel biomimetic coatings, able to guide tissue regeneration especially in cardiovascular implant industry, where in situ vascular regeneration remains an unmet challenge. Experimental Scaffold