Beilstein J. Nanotechnol.2014,5, 1580–1589, doi:10.3762/bjnano.5.170
fluorescence quenching of the coumarin moiety. However, fluorescence is activated (on) and significantly enhanced inside the cells by glutathione-initiated dissociation.
Donor–acceptor hybrids based on exfoliated graphene
However, as mentioned earlier, the surface defects in the sp2-network of GO influence the
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Scheme 1:
General chemical modification routes for exfoliated graphene sheets. (a) [3 + 2] 1,3-dipolar cycloa...
Beilstein J. Nanotechnol.2014,5, 1477–1490, doi:10.3762/bjnano.5.161
the reductive capacity of glutathione (the cytosolic concentration of which is between 5 and 10 mM) may be used to displace a fluorescence resonance energy transfer (FRET) acceptor on the surface of the NP as confirmation of a successful NP localization to the cytosol [55]. Such experiments are in
to positively charged NPs [121][122]. iii) Lipids present in membranes or second-messenger lipids wrap around NPs driven by hydrophilic/hydrophobic interaction and often result in formation of micelles [123][124]. iv) Thiols, present in glutathione or reduced proteins bind to the surface of noble
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Figure 1:
An overview of the “zoo” of different NPs concerning their composition, functionality, and fields o...