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Search for "liposomes" in Full Text gives 73 result(s) in Beilstein Journal of Nanotechnology.

Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations

  • Jaison Jeevanandam,
  • Ahmed Barhoum,
  • Yen S. Chan,
  • Alain Dufresne and
  • Michael K. Danquah

Beilstein J. Nanotechnol. 2018, 9, 1050–1074, doi:10.3762/bjnano.9.98

Graphical Abstract
  • structures such as dendrimers, micelles, liposomes and polymer NPs. (iv) Composite-based nanomaterials: Composite NMs are multiphase NPs and NSMs with one phase on the nanoscale dimension that can either combine NPs with other NPs or NPs combined with larger or with bulk-type materials (e.g., hybrid
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Published 03 Apr 2018

Association of aescin with β- and γ-cyclodextrins studied by DFT calculations and spectroscopic methods

  • Ana I. Ramos,
  • Pedro D. Vaz,
  • Susana S. Braga and
  • Artur M. S. Silva

Beilstein J. Nanotechnol. 2017, 8, 348–357, doi:10.3762/bjnano.8.37

Graphical Abstract
  • resource to controlled release strategies, which can be achieved by encapsulating aescin into liposomes [2][3], phytosomes (phospholipidic self-emulsifying particles) [10], zeolites [11], poly(lactic co-glycolic acid) nanoparticles [12] or cyclodextrins. Cyclodextrins are cyclic oligosaccharides, typically
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Published 03 Feb 2017

Nanoscale isoindigo-carriers: self-assembly and tunable properties

  • Tatiana N. Pashirova,
  • Andrei V. Bogdanov,
  • Lenar I. Musin,
  • Julia K. Voronina,
  • Irek R. Nizameev,
  • Marsil K. Kadirov,
  • Vladimir F. Mironov,
  • Lucia Ya. Zakharova,
  • Shamil K. Latypov and
  • Oleg G. Sinyashin

Beilstein J. Nanotechnol. 2017, 8, 313–324, doi:10.3762/bjnano.8.34

Graphical Abstract
  • and hydrogen bonding. Another strategy is the use of soft matter (micelles, emulsions, dendrimers, nanospheres, solid lipid nanoparticles or liposomes) as the delivery vehicle. These studies have been encouraged by the possibility to prevent side effects, to increase drug bioavailability, to decrease
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Published 01 Feb 2017

Graphene-enhanced plasmonic nanohole arrays for environmental sensing in aqueous samples

  • Christa Genslein,
  • Peter Hausler,
  • Eva-Maria Kirchner,
  • Rudolf Bierl,
  • Antje J. Baeumner and
  • Thomas Hirsch

Beilstein J. Nanotechnol. 2016, 7, 1564–1573, doi:10.3762/bjnano.7.150

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  • enhanced to achieve low detection limits. To address this issue nanomaterials ranging from metallic nanoparticles, carbon-based structures to liposomes were used [10][11][12]. Plasmonic transducers are sensitive to changes of optical properties such as the dielectric constant and hence the refractive index
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Published 01 Nov 2016

On the pathway of cellular uptake: new insight into the interaction between the cell membrane and very small nanoparticles

  • Claudia Messerschmidt,
  • Daniel Hofmann,
  • Anja Kroeger,
  • Katharina Landfester,
  • Volker Mailänder and
  • Ingo Lieberwirth

Beilstein J. Nanotechnol. 2016, 7, 1296–1311, doi:10.3762/bjnano.7.121

Graphical Abstract
  • serum-containing media [8][11][13][14]. Interestingly, studies using cell models like artificial liposomes or polymersomes report the uptake of SiNPs into these structures in a size-dependent manner [15]. Different groups report that silica NPs are cytotoxic in a dose, size and time-dependent manner
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Published 16 Sep 2016

Reconstitution of the membrane protein OmpF into biomimetic block copolymer–phospholipid hybrid membranes

  • Matthias Bieligmeyer,
  • Franjo Artukovic,
  • Stephan Nussberger,
  • Thomas Hirth,
  • Thomas Schiestel and
  • Michaela Müller

Beilstein J. Nanotechnol. 2016, 7, 881–892, doi:10.3762/bjnano.7.80

Graphical Abstract
  • strength up to 10 times larger than that of phospholipid bilayers [18][19][20][21][22][23][24]. Vesicles formed by synthetic block polymers (polymersomes) can be modified in a similar way as vesicles made from phospholipids (liposomes) [25][26][27][28]. Although polymer membranes are generally thicker than
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Published 21 Jun 2016

Tight junction between endothelial cells: the interaction between nanoparticles and blood vessels

  • Yue Zhang and
  • Wan-Xi Yang

Beilstein J. Nanotechnol. 2016, 7, 675–684, doi:10.3762/bjnano.7.60

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  • -Newtonian behavior. Their shear viscosity increases with the increase of nanoparticle volume fraction and with a drop in temperature [86]. There is also an interaction between shear stress and cell response to NPs. A study considering cell response to PEGylated poly(dopamine)-coated liposomes under shear
  • stress found that without shear stress, the cellular uptake/association of both PDA-coated liposomes (LPDA) and LPDA-PEG for hepatocytes were quite similar, while myoblasts preferred to internalize/associate with LPDA. However, under shear stress, hepatocytes showed its preference to LPDA after 30 min
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Published 06 May 2016

Comparison of the interactions of daunorubicin in a free form and attached to single-walled carbon nanotubes with model lipid membranes

  • Dorota Matyszewska

Beilstein J. Nanotechnol. 2016, 7, 524–532, doi:10.3762/bjnano.7.46

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  • includes liposomes, which are commercially available daunorubicin formulation (Daunoxome®) used in the treatment of Kaposi’s sarcoma [6]. Despite that, there are still numerous studies on the improvement of this drug delivery system aiming at enhancing drug loading into cells by using specific interactions
  • between targeting agents and their receptors, such as for example folates and transferrin [7][8]. Additionally, liposomes are also prepared in such a way that simultaneous loading of two drugs into a liposome in order to improve the efficiency of the treatment is possible [9]. Dual drug loading is also
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Published 08 Apr 2016

Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory

  • Marina E. Vance,
  • Todd Kuiken,
  • Eric P. Vejerano,
  • Sean P. McGinnis,
  • Michael F. Hochella Jr.,
  • David Rejeski and
  • Matthew S. Hull

Beilstein J. Nanotechnol. 2015, 6, 1769–1780, doi:10.3762/bjnano.6.181

Graphical Abstract
  • advertising to contain metal and metal oxide nanomaterials, silicon-based nanomaterials (mostly SiO2 nanoparticles), and a variety of other nanomaterial components (organics, ceramics, polymers, clays, nanocellulose, liposomes, nano micelles, carnauba wax, etc.) have been growing in popularity. During the
  • nanomaterials (CNT = carbon nanotubes). Major nanomaterial composition groups over time. Carbon = carbonaceous nanomaterials (carbon black, carbon nanotubes, fullerenes, graphene). Other = organics, ceramics, polymers, clays, nanocellulose, liposomes, nano micelles, carnauba wax, etc. Note the difference in
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Published 21 Aug 2015

Analyzing collaboration networks and developmental patterns of nano-enabled drug delivery (NEDD) for brain cancer

  • Ying Huang,
  • Jing Ma,
  • Alan L. Porter,
  • Seokbeom Kwon and
  • Donghua Zhu

Beilstein J. Nanotechnol. 2015, 6, 1666–1676, doi:10.3762/bjnano.6.169

Graphical Abstract
  • exposure of the pharmaceutical through controlled release. Thus, NEDD provides a novel approach to medical therapy, including treatment of chronic diseases and genetic disorders [5]. At the present, various kinds of nanoparticles have been developed as drug carriers, such as liposomes, micelles, polymeric
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Published 31 Jul 2015

Fulleropeptide esters as potential self-assembled antioxidants

  • Mira S. Bjelaković,
  • Tatjana J. Kop,
  • Jelena Đorđević and
  • Dragana R. Milić

Beilstein J. Nanotechnol. 2015, 6, 1065–1071, doi:10.3762/bjnano.6.107

Graphical Abstract
  • significant antioxidant capacity to remove hydroxyl and superoxide radicals when incorporated into liposomes [23]. With respect to the design and synthesis of fulleropyrrolidine-based hybrids, we previously showed the synthesis of fullerene–steroid esters [24] and triple hybrids consisting of fullerene
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Published 27 Apr 2015

Pulmonary surfactant augments cytotoxicity of silica nanoparticles: Studies on an in vitro air–blood barrier model

  • Jennifer Y. Kasper,
  • Lisa Feiden,
  • Maria I. Hermanns,
  • Christoph Bantz,
  • Michael Maskos,
  • Ronald E. Unger and
  • C. James Kirkpatrick

Beilstein J. Nanotechnol. 2015, 6, 517–528, doi:10.3762/bjnano.6.54

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  • transfection and delivery studies using mainly cationic polymers or liposomes [8][24]. The positive NP surface charge enables better cellular contact and/or uptake than negatively charged or neutral molecules [25]. Nevertheless, the use of these positively charged drug and gene delivery carriers remains
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Published 20 Feb 2015

Release behaviour and toxicity evaluation of levodopa from carboxylated single-walled carbon nanotubes

  • Julia M. Tan,
  • Jhi Biau Foo,
  • Sharida Fakurazi and
  • Mohd Zobir Hussein

Beilstein J. Nanotechnol. 2015, 6, 243–253, doi:10.3762/bjnano.6.23

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  • a combination of both traditional medical technology and nanotechnology, with the exploitation of nanosized materials of dimensions less than 100 nm. One such nanomedical approach to drug delivery technology that has made a great impact was the first demonstration utilizing liposomes as drug
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Published 22 Jan 2015

Interaction of dermatologically relevant nanoparticles with skin cells and skin

  • Annika Vogt,
  • Fiorenza Rancan,
  • Sebastian Ahlberg,
  • Berouz Nazemi,
  • Chun Sik Choe,
  • Maxim E. Darvin,
  • Sabrina Hadam,
  • Ulrike Blume-Peytavi,
  • Kateryna Loza,
  • Jörg Diendorf,
  • Matthias Epple,
  • Christina Graf,
  • Eckart Rühl,
  • Martina C. Meinke and
  • Jürgen Lademann

Beilstein J. Nanotechnol. 2014, 5, 2363–2373, doi:10.3762/bjnano.5.245

Graphical Abstract
  • liposomes or transferosomes. [1][2]. Although increasing reports suggest that barrier translocation of solid particles occurs especially when the skin barrier is disrupted, the penetration of solid particles into the viable epidermis seems to be limited. Figure 1 illustrates the experimental set-up that we
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Published 08 Dec 2014

Nanobioarchitectures based on chlorophyll photopigment, artificial lipid bilayers and carbon nanotubes

  • Marcela Elisabeta Barbinta-Patrascu,
  • Stefan Marian Iordache,
  • Ana Maria Iordache,
  • Nicoleta Badea and
  • Camelia Ungureanu

Beilstein J. Nanotechnol. 2014, 5, 2316–2325, doi:10.3762/bjnano.5.240

Graphical Abstract
  • , which has been exploited in the preparation of anti-aging cosmetics and sunscreen creams to protect skin against free radicals formed by the body or by UV sunlight [10]. The goal of this work is to achieve antioxidant and antibacterial bionanomaterials based on liposomes and carbon nanotubes, which
  • could open new perspectives for biomedical and biotechnological applications. The increased interest in use of phospholipids is due to the fact that they are basic structural components of biomembranes and artificial lipid membranes (liposomes). Liposomes are spherical, soft-matter vesicles composed of
  • one or more lipid membranes (called lamellae) separated by aqueous compartments [22], with the structure of their lipid bilayers resembling that of cell membranes. In this work, we present the preparation of complex biocomposites based on liposomes and carbon nanotubes. Chlorophyll a is used as a
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Published 02 Dec 2014

Anticancer efficacy of a supramolecular complex of a 2-diethylaminoethyl–dextran–MMA graft copolymer and paclitaxel used as an artificial enzyme

  • Yasuhiko Onishi,
  • Yuki Eshita,
  • Rui-Cheng Ji,
  • Masayasu Onishi,
  • Takashi Kobayashi,
  • Masaaki Mizuno,
  • Jun Yoshida and
  • Naoji Kubota

Beilstein J. Nanotechnol. 2014, 5, 2293–2307, doi:10.3762/bjnano.5.238

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  • polyglutamate [43] and albumin [44], encapsulated in cationic liposomes [45], or PEG-polyaspartate [46]. By using these carriers, PTX is thought to be transported into and released directly in cells, thus improving its efficacy. However, the DDMC/PTX complex will be not degraded in the cell, and its efficacy
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Published 01 Dec 2014

The cell-type specific uptake of polymer-coated or micelle-embedded QDs and SPIOs does not provoke an acute pro-inflammatory response in the liver

  • Markus Heine,
  • Alexander Bartelt,
  • Oliver T. Bruns,
  • Denise Bargheer,
  • Artur Giemsa,
  • Barbara Freund,
  • Ludger Scheja,
  • Christian Waurisch,
  • Alexander Eychmüller,
  • Rudolph Reimer,
  • Horst Weller,
  • Peter Nielsen and
  • Joerg Heeren

Beilstein J. Nanotechnol. 2014, 5, 1432–1440, doi:10.3762/bjnano.5.155

Graphical Abstract
  • -inflammatory factors such as TNFα, a cytokine, provoking collagen synthesis and fibrosis [34]. To clarify the quantitative role of Kupffer cells for potential harmful effects of injected nanocrystals, clodronate containing liposomes were injected to ablate Kupffer cell populations in the liver selectively [35
  • , mice were injected intravenously in the tail vein with 200 µL Clodronate liposome solution (ClodronateLiposomes.org, Amsterdam, Netherland) or empty liposomes as control two days prior to the experiments. Gene expression analysis Gene expression analysis was performed as described [39]. Briefly, total
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Published 02 Sep 2014

Model systems for studying cell adhesion and biomimetic actin networks

  • Dorothea Brüggemann,
  • Johannes P. Frohnmayer and
  • Joachim P. Spatz

Beilstein J. Nanotechnol. 2014, 5, 1193–1202, doi:10.3762/bjnano.5.131

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  • the possibility to isolate membrane proteins, such as integrin, from cells and to embed them into lipid structures ranging from planar bilayers and small liposomes to giant unilamellar vesicles. This procedure has enabled studies on the functional properties of membrane proteins in a defined
  • platelet aggregation and has been well characterised. The liposomes, into which the integrins were incorporated, had diameters of 40 ± 8 nm and can be characterised as small liposomes. Integrin reconstitution was carried out by a detergent-dialysis method. During reconstitution the purified integrins were
  • confirmed by specific binding to fibrinogen [33]. Triton X-100 is another detergent that is widely used for the reconstitution of numerous membrane proteins into liposomes since the 1980s [32][35][36]. This detergent has the tendency to form large micelles, which cannot be removed by dialysis. An efficient
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Published 01 Aug 2014

Nanodiamond-DGEA peptide conjugates for enhanced delivery of doxorubicin to prostate cancer

  • Amanee D Salaam,
  • Patrick Hwang,
  • Roberus McIntosh,
  • Hadiyah N Green,
  • Ho-Wook Jun and
  • Derrick Dean

Beilstein J. Nanotechnol. 2014, 5, 937–945, doi:10.3762/bjnano.5.107

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  • tumor types [6][7][8][9]. Currently, there are several clinically approved nanoparticle-based cancer drugs using liposomes, nanoparticle albumin-bound (nab) technology, dendrimers, polymeric, carbon, and metal nanoparticles [6][8]. Gold nanorods, iron magnetic nanoparticles, polymer nanospheres, lipids
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Published 01 Jul 2014

Cyclodextrin-poly(ε-caprolactone) based nanoparticles able to complex phenolphthalein and adamantyl carboxylate

  • Daniela Ailincai and
  • Helmut Ritter

Beilstein J. Nanotechnol. 2014, 5, 651–657, doi:10.3762/bjnano.5.76

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  • nanovesicles based on natural macromolecular compounds, liposomes formed by autoassemble of phospholipids in aqueous medium [1], and nanovesicles formed by the autoassemble of synthetic amphiphilic copolymers, polymersomes [2]. There is a broad variety of conditions which have to be met, both for nanoparticles
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Published 16 May 2014

Nanoscopic surfactant behavior of the porin MspA in aqueous media

  • Ayomi S. Perera,
  • Hongwang Wang,
  • Tej B. Shrestha,
  • Deryl L. Troyer and
  • Stefan H. Bossmann

Beilstein J. Nanotechnol. 2013, 4, 278–284, doi:10.3762/bjnano.4.30

Graphical Abstract
  • = 0.31 and the experimental finding that vesicles are formed, which requires 0.5 < P < 1. Charge attraction/repulsion [30] apparently only plays a minor role, since the observed formation of liposomes does not strongly depend on the ionic strengths of the aqueous medium. The anisotropy of the negative
  • . Since MspA is a large surfactant, the requirement for thermal activation is comprehensible. It should also be noted that many classic vesicles/liposomes are not in their thermodynamic minimum [32]. Conclusion TEM has provided experimental evidence that the mycobacterial porin MspA forms vesicles at low
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Published 25 Apr 2013

Magnetic-Fe/Fe3O4-nanoparticle-bound SN38 as carboxylesterase-cleavable prodrug for the delivery to tumors within monocytes/macrophages

  • Hongwang Wang,
  • Tej B. Shrestha,
  • Matthew T. Basel,
  • Raj K. Dani,
  • Gwi-Moon Seo,
  • Sivasai Balivada,
  • Marla M. Pyle,
  • Heidy Prock,
  • Olga B. Koper,
  • Prem S. Thapa,
  • David Moore,
  • Ping Li,
  • Viktor Chikan,
  • Deryl L. Troyer and
  • Stefan H. Bossmann

Beilstein J. Nanotechnol. 2012, 3, 444–455, doi:10.3762/bjnano.3.51

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  • vehicles that can incorporate SN38 by chemical conjugation or physical entrapment. Polymeric micelles, liposomes and thermally sensitive polymer-based nanoparticles, as well as multi-armed-PEG-functionalized nanographene oxide, have been used as carriers for the delivery of SN38 into biological systems [21
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Published 13 Jun 2012

Microfluidic anodization of aluminum films for the fabrication of nanoporous lipid bilayer support structures

  • Jaydeep Bhattacharya,
  • Alexandre Kisner,
  • Andreas Offenhäusser and
  • Bernhard Wolfrum

Beilstein J. Nanotechnol. 2011, 2, 104–109, doi:10.3762/bjnano.2.12

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  • whole system was then cured at 60 °C for 60 min. The lipid bilayer on the modified nanoporous alumina surface was prepared by the method of liposomal fusion [39]. The liposomes were prepared from 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC, Avanti Polar Lipids, U.S.A.) by the following method
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Published 11 Feb 2011
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