Comparison of the interactions of daunorubicin in a free form and attached to single-walled carbon nanotubes with model lipid membranes

• Dorota Matyszewska

Beilstein J. Nanotechnol. 2016, 7, 524–532, doi:10.3762/bjnano.7.46

• -DNR monolayer and incorporated drug in the free form. This proves that the amount of the drug in the model membrane is similar for both types of the drug delivery: direct or bound to the nanocarrier. However, basing on the results of monolayer studies, the effect of SWCNTs-DNR adducts on the

• . Moreover, it was shown that the surface concentration of the drug on the electrode surface is similar for both the drug in a free form and the drug–nanocarrier adduct. This observation proves that application of single-walled carbon nanotubes as drug delivery system allows for the transport of the

PLGA nanoparticles as a platform for vitamin D-based cancer therapy

• Maria J. Ramalho,
• Joana A. Loureiro,
• Bárbara Gomes,
• Manuela F. Frasco,
• Manuel A. N. Coelho and
• M. Carmo Pereira

Beilstein J. Nanotechnol. 2015, 6, 1306–1318, doi:10.3762/bjnano.6.135

• (Figure 1, white arrow) [29]. Both forms of vitamin D3 were used for the formulation of the nanocarrier system and variations in the encapsulation efficiency and loading capacity were noticed. The observed differences may be based on their chemical structure, since calcitriol has two extra hydroxy groups

Release behaviour and toxicity evaluation of levodopa from carboxylated single-walled carbon nanotubes

• Julia M. Tan,
• Jhi Biau Foo,
• Sharida Fakurazi and
• Mohd Zobir Hussein

Beilstein J. Nanotechnol. 2015, 6, 243–253, doi:10.3762/bjnano.6.23

• groups from carboxylated CNTs. In this case, the solubility of the nanocarrier increases with an increase in pH value [24], resulting in more carboxylate anions (–COO−) produced in pH 7.4 as compared to pH 4.8. In addition, the different release mechanisms of LD at different pH levels could be also due

• therapeutic effect [26] and may benefit the treatment of PD. Release kinetics of LD To further analyse the release kinetics of LD from the SWCNT–COOH nanocarrier, pseudo-first-order (Equation 1), pseudo-second-order (Equation 2) and a parabolic diffusion equation (Equation 3) were adopted [3][27][28] as

• , R2, rate constant and half-time resulting from the pseudo-second-order model fits are also presented in Table 3. The second-order reaction suggests that the release of LD from its nanocarrier is dependent on the concentration, and that the half-time should increase as the process continues [29

Synthesis of boron nitride nanotubes and their applications

• Saban Kalay,
• Zehra Yilmaz,
• Ozlem Sen,
• Melis Emanet,
• Emine Kazanc and
• Mustafa Çulha

Beilstein J. Nanotechnol. 2015, 6, 84–102, doi:10.3762/bjnano.6.9

• multifunctional, BNNT-based nanocarrier was synthesized using an Fe catalyst to render them magnetic and coated with PEI whereby QDs were attached to the PEI-coated BNNTs [83]. The cellular uptake of the BNNTs was tracked by QDs which revealed that the cellular uptake of the BNNTs depends upon the distance from

Anticancer efficacy of a supramolecular complex of a 2-diethylaminoethyl–dextran–MMA graft copolymer and paclitaxel used as an artificial enzyme

• Yasuhiko Onishi,
• Yuki Eshita,
• Rui-Cheng Ji,
• Masayasu Onishi,
• Takashi Kobayashi,
• Masaaki Mizuno,
• Jun Yoshida and
• Naoji Kubota

Beilstein J. Nanotechnol. 2014, 5, 2293–2307, doi:10.3762/bjnano.5.238

• micelles carrying a drug, they have been shown to be transported to and act on not only endosomes and lysosomes but also the Golgi body and mitochondria [4]. A block copolymer micelle can be used to deliver a hydrophobic drug as a nanocarrier with water-soluble biological affinity. Knowledge of the