Surface characterization of nanoparticles using near-field light scattering

• Eunsoo Yoo,
• Yizhong Liu,
• Chukwuazam A. Nwasike,
• Sebastian R. Freeman,
• Brian C. DiPaolo,
• Bernardo Cordovez and
• Amber L. Doiron

Beilstein J. Nanotechnol. 2018, 9, 1228–1238, doi:10.3762/bjnano.9.114

• , namely uncoated superparamagnetic iron oxide nanoparticles, polyethylene glycol-coated superparamagnetic iron oxide nanoparticles, and interpolymer complex-superparamagnetic iron oxide nanoparticles, were studied for changes in collective size and surface properties using an analysis of particle velocity

BN/Ag hybrid nanomaterials with petal-like surfaces as catalysts and antibacterial agents

• Konstantin L. Firestein,
• Denis V. Leybo,
• Alexander E. Steinman,
• Andrey M. Kovalskii,
• Andrei T. Matveev,
• Anton M. Manakhov,
• Irina V. Sukhorukova,
• Pavel V. Slukin,
• Nadezda K. Fursova,
• Sergey G. Ignatov,
• Dmitri V. Golberg and
• Dmitry V. Shtansky

Beilstein J. Nanotechnol. 2018, 9, 250–261, doi:10.3762/bjnano.9.27

• produce grams of BN/Ag HNMs in a single experimental run (referred to as CVD BN/Ag HNMs). To prepare BN/Ag HNMs via UV decomposition of AgNO3 (abbreviated as UV BN/Ag HNMs), we have dispersed 100 mg of raw BN NPs in 50 mL of polyethylene glycol 400 (PEG-400) using an ultrasonic homogenizer Bandelin HD2200

Refractive index sensing and surface-enhanced Raman spectroscopy using silver–gold layered bimetallic plasmonic crystals

• Somi Kang,
• Sean E. Lehman,
• Matthew V. Schulmerich,
• An-Phong Le,
• Tae-woo Lee,
• Stephen K. Gray,
• Rohit Bhargava and
• Ralph G. Nuzzo

Beilstein J. Nanotechnol. 2017, 8, 2492–2503, doi:10.3762/bjnano.8.249

• % methylhydrosiloxane)-(dimethylsiloxane) (HMS-301), poly(7–8% vinylmethylsiloxane)-(dimethylsiloxane), (VDT-731), platinum divinyltetramethyldisiloxane (SIP6831.1) and (1,3,5,7-tetravinyl-1,3,5,7-tetramethylcyclotetrasiloxane) (7900), were purchased from Gelest. Polyethylene glycol (PEG, MW = 10,000 g/mol) and

Imidazolium-based ionic liquids used as additives in the nanolubrication of silicon surfaces

• Patrícia M. Amorim,
• Ana M. Ferraria,
• Rogério Colaço,
• Luís C. Branco and
• Benilde Saramago

Beilstein J. Nanotechnol. 2017, 8, 1961–1971, doi:10.3762/bjnano.8.197

• polyethylene glycol (PEG) to lubricate Si surfaces. The friction coefficients were measured in a nanotribometer. The viscosity of the PEG + IL mixtures as well as their contact angles on the Si surface were measured. The topography and chemical composition of the substrates surfaces were determined with atomic

Cationic PEGylated polycaprolactone nanoparticles carrying post-operation docetaxel for glioma treatment

• Cem Varan and
• Erem Bilensoy

Beilstein J. Nanotechnol. 2017, 8, 1446–1456, doi:10.3762/bjnano.8.144

• reported to be nontoxic, biocompatible and biodegradable and is approved for therapeutic use in humans by the FDA. PCL can be copolymerized with other synthetic polymers such as polyethylene glycol (PEG) and polyethylene oxide (PEO) to obtain new polycaprolactone derivatives with various novel properties

Micro- and nano-surface structures based on vapor-deposited polymers

• Hsien-Yeh Chen

Beilstein J. Nanotechnol. 2017, 8, 1366–1374, doi:10.3762/bjnano.8.138

• for the pattern formation of polyethylene glycol (PEG)-like polymer derivatives to guide fibroblast attachment [21]. A photodefinable polymer of poly(4-benzoyl-p-xylylene-co-p-xylylene) was synthesized by CVD, and a combined soft lithographical and UV light process was performed to create the

Nanoscale isoindigo-carriers: self-assembly and tunable properties

• Tatiana N. Pashirova,
• Andrei V. Bogdanov,
• Lenar I. Musin,
• Julia K. Voronina,
• Irek R. Nizameev,
• Marsil K. Kadirov,
• Vladimir F. Mironov,
• Lucia Ya. Zakharova,
• Shamil K. Latypov and
• Oleg G. Sinyashin

Beilstein J. Nanotechnol. 2017, 8, 313–324, doi:10.3762/bjnano.8.34

• isoindigo scaffold was functionalized with carbohydrate substituents [36][37]. Over the last three decades, extensive research in nanomedicine led to several strategies to improve drug biocompatibility and drug delivery efficacy (e.g., synthesis of polymer–drug conjugates, such as polyethylene glycol

Comparison of four functionalization methods of gold nanoparticles for enhancing the enzyme-linked immunosorbent assay (ELISA)

• Paula Ciaurriz,
• Fátima Fernández,
• Edurne Tellechea,
• Jose F. Moran and
• Aaron C. Asensio

Beilstein J. Nanotechnol. 2017, 8, 244–253, doi:10.3762/bjnano.8.27

• -polyethylene glycol-dithiol, was used to control the orientation of the molecules on the surface of the nanoparticle. Hydrazide is able to react with aldehyde groups that can be generated by oxidizing the carbohydrates of glycosylated proteins, such as antibodies [20]. For this purpose, antibody and HRP

Effective intercalation of zein into Na-montmorillonite: role of the protein components and use of the developed biointerfaces

• Ana C. S. Alcântara,
• Margarita Darder,
• Pilar Aranda and
• Eduardo Ruiz-Hitzky

Beilstein J. Nanotechnol. 2016, 7, 1772–1782, doi:10.3762/bjnano.7.170

• examples, organoclays containing alkylammonium surfactant species [20][22] or polyethylene glycol as plasticizer [21] were required to produce the zein-based materials. Nevertheless, the process of formation of zein–montmorillonite biohybrids making use of sodium-exchanged montmorillonite (Na

Comparison of the interactions of daunorubicin in a free form and attached to single-walled carbon nanotubes with model lipid membranes

• Dorota Matyszewska

Beilstein J. Nanotechnol. 2016, 7, 524–532, doi:10.3762/bjnano.7.46

• conjugated to either polyethylene glycol (PEG) functionalized single-walled carbon nanotubes (SWCNTs) [20] or to aptamer-wrapped SWCNTs via π–π interactions. In both cases the cytotoxicity of the conjugates was verified on the selected cancer cell lines. In this study the influence of both free daunorubicin

Green and energy-efficient methods for the production of metallic nanoparticles

• Mitra Naghdi,
• Mehrdad Taheran,
• Satinder K. Brar,
• M. Verma,
• R. Y. Surampalli and
• J. R. Valero

Beilstein J. Nanotechnol. 2015, 6, 2354–2376, doi:10.3762/bjnano.6.243

• , they produced spherical Ag NPs with an average diameter of 26 nm, and polydispersity of 2.3%. They also investigated the capability of different ionic and non-ionic surfactants and also polyethylene glycol (PEG) and polyvinylpyrrolidone (PVP) in surface modification and stabilization of Ag NPs produced

• their FTIR results, different sugars, amino acids and fatty acids are responsible for the stabilization processes. They also observed that by changing the concentration of precursor, one can obtain NPs with average particle diameter from 7.8 to 4.8 nm [89]. Polyols Shameli et al. used polyethylene

• glycol (PEG) and β-D-glucose as stabilizing and reducing agents, respectively, to produce colloidal Ag NPs from AgNO3 at 60 °C. They studied the properties of Ag NPs at different reaction times and found that the average particle sizes were 10.60, 11.23, 15.30 and 25.31 nm for different mixing times of 3

Nanofibers for drug delivery – incorporation and release of model molecules, influence of molecular weight and polymer structure

• Jakub Hrib,
• Jakub Sirc,
• Radka Hobzova,
• Zuzana Hampejsova,
• Zuzana Bosakova,
• Marcela Munzarova and
• Jiri Michalek

Beilstein J. Nanotechnol. 2015, 6, 1939–1945, doi:10.3762/bjnano.6.198

• amount of released molecules after 72 hours. However, the influence of the chemical composition of nanofibers was even more distinct – the highest amount of polyethylene glycol molecules released from polyvinyl alcohol nanofibers, the lowest amount from polylactide nanofibers. Keywords: nanofibers

• molecular weights of 2,000, 6,000, 10,000 and 20,000 g/mol were selected as model molecules. Polyethylene glycol (PEG) is a hydrophilic polyether commercially available in various molecular weights with narrow distribution. It is widely used in various medical applications, for example as surfactant

• into aqueous media in which the solubility of such drugs are very low. Conclusion The release kinetics of polyethylene glycol molecules of various molecular weights from nanofibers prepared from polycaprolactone, polylactide and polyvinyl alcohol were assessed. The release rate and the total released

From lithium to sodium: cell chemistry of room temperature sodium–air and sodium–sulfur batteries

• Philipp Adelhelm,
• Pascal Hartmann,
• Conrad L. Bender,
• Martin Busche,
• Christine Eufinger and
• Juergen Janek

Beilstein J. Nanotechnol. 2015, 6, 1016–1055, doi:10.3762/bjnano.6.105

Protein corona – from molecular adsorption to physiological complexity

• Lennart Treuel,
• Dominic Docter,
• Michael Maskos and
• Roland H. Stauber

Beilstein J. Nanotechnol. 2015, 6, 857–873, doi:10.3762/bjnano.6.88

• indeed alters the cellular response to NPs. For example, NP opsonization with immunoglobulin reportedly promoted receptor-mediated phagocytosis by macrophages [155]. The presence of polyethylene glycol (PEG) was shown to suppress protein absorption resulting in a decreased uptake by macrophages [142] and

Novel ZnO:Ag nanocomposites induce significant oxidative stress in human fibroblast malignant melanoma (Ht144) cells

• Syeda Arooj,
• Samina Nazir,
• Akhtar Nadhman,
• Nafees Ahmad,
• Bakhtiar Muhammad,
• Ishaq Ahmad,
• Kehkashan Mazhar and
• Rashda Abbasi

Beilstein J. Nanotechnol. 2015, 6, 570–582, doi:10.3762/bjnano.6.59

• potential cytotoxicity, biocompatibility and biosafety of such particles in vitro as well as in vivo. Experimental Reagents Acetic acid, DMSO, ethylenediaminetetraacetic acid disodium salt dihydrate (Na2EDTA·2H2O), FeSO4, L-glutamine, hydrochloric acid (HCl), mannitol, penicillin-G, polyethylene glycol (PEG

Pulmonary surfactant augments cytotoxicity of silica nanoparticles: Studies on an in vitro air–blood barrier model

• Jennifer Y. Kasper,
• Lisa Feiden,
• Maria I. Hermanns,
• Christoph Bantz,
• Michael Maskos,
• Ronald E. Unger and
• C. James Kirkpatrick

Beilstein J. Nanotechnol. 2015, 6, 517–528, doi:10.3762/bjnano.6.54

• (3.7%) in CS buffer (PIPES 0.1 M, EGTA 1 mM, 4% polyethylene glycol 800, NaOH 0.1 M) for 20 min at room temperature, and washed three times with PBS. Cell membranes were then permeabilized with 0.2% Triton X-100 in PBS for 10 min. After washing three times in PBS cells were stained with primary

Comparative evaluation of the impact on endothelial cells induced by different nanoparticle structures and functionalization

• Lisa Landgraf,
• Ines Müller,
• Peter Ernst,
• Miriam Schäfer,
• Christina Rosman,
• Isabel Schick,
• Oskar Köhler,
• Hartmut Oehring,
• Vladimir V. Breus,
• Thomas Basché,
• Carsten Sönnichsen,
• Wolfgang Tremel and
• Ingrid Hilger

Beilstein J. Nanotechnol. 2015, 6, 300–312, doi:10.3762/bjnano.6.28

• cetyltrimetylammonium bromide (CTAB) in water. Furthermore, we investigated the effects of GNP that were linked to thiol-terminated polyethylene glycol (SH-PEG, MW of PEG: 5 kDa) with different reactive groups: cationic (-NH2), anionic (-COOH) or neutral (-OCH3). 2) Asymmetric Au@metal oxide nanoparticles have an

Mechanical properties of MDCK II cells exposed to gold nanorods

• Anna Pietuch,
• Bastian Rouven Brückner,
• David Schneider,
• Marco Tarantola,
• Christina Rosman,
• Carsten Sönnichsen and
• Andreas Janshoff

Beilstein J. Nanotechnol. 2015, 6, 223–231, doi:10.3762/bjnano.6.21

• either cetyl-trimethylammonium bromide (CTAB) or biocompatible polyethylene glycol (PEG) coated gold nanoparticles in different concentrations. We also examined structural rearrangement of the cytoskeleton via fluorescence microscopy and by that tried to gain a deeper understanding of how gold

• of gold nanorods were obtained from UV–vis spectroscopy using their optical extinction value at 400 nm and a molar extinction coefficient of 1.1 × 109 Lmol−1cm−1 assuming the aforementioned particle size found by TEM. In order to replace the CTAB, functionalized polyethylene glycol thiols (X-PEG-SH

Electrostatic interplay: The interaction triangle of polyamines, silicic acid, and phosphate studied through turbidity measurements, silicomolybdic acid test, and ²⁹Si NMR spectroscopy

• Anne Jantschke,
• Katrin Spinde and
• Eike Brunner

Beilstein J. Nanotechnol. 2014, 5, 2026–2035, doi:10.3762/bjnano.5.211

• negatively charged silica particles [18][20]. Subsequent in vitro studies support the idea of polyamine-stabilized sols [21][22]. In contrast to the charged PAH, uncharged polymers such as polyvinylpyrrolidone or polyethylene glycol cannot undergo such a self-assembly process driven by electrostatic

PVP-coated, negatively charged silver nanoparticles: A multi-center study of their physicochemical characteristics, cell culture and in vivo experiments

• Sebastian Ahlberg,
• Alexandra Antonopulos,
• Jörg Diendorf,
• Ralf Dringen,
• Matthias Epple,
• Rebekka Flöck,
• Wolfgang Goedecke,
• Christina Graf,
• Nadine Haberl,
• Jens Helmlinger,
• Fabian Herzog,
• Frederike Heuer,
• Stephanie Hirn,
• Christian Johannes,
• Stefanie Kittler,
• Manfred Köller,
• Katrin Korn,
• Wolfgang G. Kreyling,
• Fritz Krombach,
• Jürgen Lademann,
• Kateryna Loza,
• Eva M. Luther,
• Marcelina Malissek,
• Martina C. Meinke,
• Daniel Nordmeyer,
• Anne Pailliart,
• Jörg Raabe,
• Fiorenza Rancan,
• Barbara Rothen-Rutishauser,
• Eckart Rühl,
• Carsten Schleh,
• Andreas Seibel,
• Christina Sengstock,
• Lennart Treuel,
• Annika Vogt,
• Katrin Weber and
• Reinhard Zellner

Beilstein J. Nanotechnol. 2014, 5, 1944–1965, doi:10.3762/bjnano.5.205

• localization of silver in the perinuclear region was observed (Figure 5A). In none of the investigated cells an indication for uptake into the nucleus was found, which is in agreement with a quantitative TEM analysis of citrate- or polyethylene glycol (PEG)-stabilized gold nanoparticles, in which no particles

Carbon-based smart nanomaterials in biomedicine and neuroengineering

• Antonina M. Monaco and
• Michele Giugliano

Beilstein J. Nanotechnol. 2014, 5, 1849–1863, doi:10.3762/bjnano.5.196

• [91] and drug delivery to substrates for biomolecular imaging [92][93], and from tissue scaffolds [94] to electrodes for neural stimulation [95]. For instance, Yang and colleagues [96] investigated the possibility of using polyethylene glycol (PEG)-coated nanographene sheets showing absorption in the

In vitro and in vivo interactions of selected nanoparticles with rodent serum proteins and their consequences in biokinetics

• Wolfgang G. Kreyling,
• Stefanie Fertsch-Gapp,
• Martin Schäffler,
• Blair D. Johnston,
• Nadine Haberl,
• Christian Pfeiffer,
• Jörg Diendorf,
• Carsten Schleh,
• Stephanie Hirn,
• Manuela Semmler-Behnke,
• Matthias Epple and
• Wolfgang J. Parak

Beilstein J. Nanotechnol. 2014, 5, 1699–1711, doi:10.3762/bjnano.5.180

• groups, but also with polyethylene glycol (PEG) or other polymers or polyelectrolytes and, finally, with tightly grafted plasma proteins (albumin or apolipoprotein E). All AuNP had been radioactively labeled with 198Au by neutron activation in a nuclear research reactor. Most of these studies were

Non-covalent and reversible functionalization of carbon nanotubes

• Antonello Di Crescenzo,
• Valeria Ettorre and
• Antonella Fontana

Beilstein J. Nanotechnol. 2014, 5, 1675–1690, doi:10.3762/bjnano.5.178

• still under investigation. Polyethylene glycol (PEG) chains with PEG repeating units as long as 8, have been demonstrated [52] to favor both self-assembly and dispersion of SWCNTs in chloroform and 1,2-dichlorobenzene once chosen a hydrophobic domain B (i.e., hexa-p-phenylene) able to establish π–π

In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far?

• Moritz Nazarenus,
• Qian Zhang,
• Mahmoud G. Soliman,
• Pablo del Pino,
• Beatriz Pelaz,
• Susana Carregal-Romero,
• Joanna Rejman,
• Barbara Rothen-Rutishauser,
• Martin J. D. Clift,
• Reinhard Zellner,
• G. Ulrich Nienhaus,
• James B. Delehanty,
• Igor L. Medintz and
• Wolfgang J. Parak

Beilstein J. Nanotechnol. 2014, 5, 1477–1490, doi:10.3762/bjnano.5.161

• efficiently [34]. Non-fouling polyethylene glycol (PEG)-modified NPs, for example, stick less to the cell plasma membrane and are, therefore, incorporated by cells less efficiently than other NPs [35][36][37] (this is also true in vivo as manifested by enhanced retention times [38]). It is clear that, while

PEGylated versus non-PEGylated magnetic nanoparticles as camptothecin delivery system

• Paula M. Castillo,
• Mario de la Mata,
• Maria F. Casula,
• José A. Sánchez-Alcázar and
• Ana P. Zaderenko

Beilstein J. Nanotechnol. 2014, 5, 1312–1319, doi:10.3762/bjnano.5.144

• surface modification of the nanoparticles by polyethylene glycol enables loading a large amount of camptothecin. While the unloaded nanoparticles do not induce apoptosis in the H460 lung cancer cell line, the camptothecin-loaded nanoparticle formulations exhibit remarkable pro-apoptotic activity. These

• ; cancer therapy; iron oxide superparamagnetic nanoparticles; polyethylene glycol; Introduction Camptothecin (CPT) is a quinoline based alkaloid, which exhibits a potent cytotoxic activity against a broad spectrum of tumours [1][2][3]. While most antineoplastic agents inhibit cancer cell proliferation by

• polyethylene glycol (PEG) as coating polymer in nano-formulations. PEG has been widely used in the formulation of nanoparticles for biomedical applications, both because of its biocompatibility and its effectiveness in camouflaging nanoparticles from opsonins [35]. Recently, it has been described that PEG