Approaches to nanostructure control and functionalizations of polymer@silica hybrid nanograss generated by biomimetic silica mineralization on a self-assembled polyamine layer

• Jian-Jun Yuan and
• Ren-Hua Jin

Beilstein J. Nanotechnol. 2011, 2, 760–773, doi:10.3762/bjnano.2.84

• , nanostructured thin films on substrates with tunable nanostructure and surface morphology are of great importance for various applications, such as photoelectronics [1], high-efficiency sensing and bioanalysis [2][3], protein adsorption [4], cell growth [5], surface wettability control [6] and liquid

Characterization of protein adsorption onto FePt nanoparticles using dual-focus fluorescence correlation spectroscopy

• Pauline Maffre,
• Karin Nienhaus,
• Faheem Amin,
• Wolfgang J. Parak and
• G. Ulrich Nienhaus

Beilstein J. Nanotechnol. 2011, 2, 374–383, doi:10.3762/bjnano.2.43

• correlation spectroscopy; human serum albumin; nanoparticle; protein adsorption; Introduction Recent years have seen enormous advances in the field of nanotechnology. A huge variety of nanoparticles (NPs), defined as objects with all three spatial dimensions in the range of 1–100 nm, has been developed, with

• understand the structural and dynamic properties of the protein corona at the molecular level. Recently, we have used quantitative fluorescence microscopy, especially fluorescence correlation spectroscopy (FCS), to study protein adsorption of human serum albumin (HSA) on polymer-coated FePt NPs with an

• protein adsorption onto the NP surfaces can be measured via an increase of τD. Knowledge of the molecule detection function (MDF), i.e., the probability to detect a fluorescence photon from a molecule at a given position in the sample volume, is key to the precise quantitative analysis of an FCS

Sensing surface PEGylation with microcantilevers

• Natalija Backmann,
• Natascha Kappeler,
• Thomas Braun,
• François Huber,
• Hans-Peter Lang,
• Christoph Gerber and
• Roderick Y. H. Lim

Beilstein J. Nanotechnol. 2010, 1, 3–13, doi:10.3762/bjnano.1.2

• highly effective at reducing protein adsorption from blood [3] thereby improving the biocompatibility of biomedical implants [4]. The protein-resistant properties of PEG have also been applied to reduce membrane fouling in ultrafiltration membranes for water purification [5]. It is important to develop a

• conjunction with protein adsorption studies, this may have specific applications as integrated (and miniaturizable) process sensors. More generally, this particular capability of microcantilever sensors may provide new insight into the biochemical and nanomechanical properties of biopolymers in vitro. For