In vitro and in vivo interactions of selected nanoparticles with rodent serum proteins and their consequences in biokinetics

• Wolfgang G. Kreyling,
• Stefanie Fertsch-Gapp,
• Martin Schäffler,
• Blair D. Johnston,
• Nadine Haberl,
• Christian Pfeiffer,
• Jörg Diendorf,
• Carsten Schleh,
• Stephanie Hirn,
• Manuela Semmler-Behnke,
• Matthias Epple and
• Wolfgang J. Parak

Beilstein J. Nanotechnol. 2014, 5, 1699–1711, doi:10.3762/bjnano.5.180

• al. [15], biokinetics of AuNP by double radio-labelling of Au cores (198Au) and their polymer surface coating (111In) with 4 nm core size; methodology was established: Ali et al. [16]; biokinetics after intravenous injection (Kreyling et al., manuscript submitted) In this series of in vivo

Different endocytotic uptake mechanisms for nanoparticles in epithelial cells and macrophages

• Dagmar A. Kuhn,
• Dimitri Vanhecke,
• Benjamin Michen,
• Fabian Blank,
• Peter Gehr,
• Alke Petri-Fink and
• Barbara Rothen-Rutishauser

Beilstein J. Nanotechnol. 2014, 5, 1625–1636, doi:10.3762/bjnano.5.174

• different NP properties, such as size, shape, material and surface coating, as well as the cell type, age, interaction with other cells and the cellular environment, influence NP uptake and the cellular behavior as well as the down-stream response of the cells [11][12][13][14][15][16]. The term endocytosis

In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far?

• Moritz Nazarenus,
• Qian Zhang,
• Mahmoud G. Soliman,
• Pablo del Pino,
• Beatriz Pelaz,
• Susana Carregal-Romero,
• Joanna Rejman,
• Barbara Rothen-Rutishauser,
• Martin J. D. Clift,
• Reinhard Zellner,
• G. Ulrich Nienhaus,
• James B. Delehanty,
• Igor L. Medintz and
• Wolfgang J. Parak

Beilstein J. Nanotechnol. 2014, 5, 1477–1490, doi:10.3762/bjnano.5.161

• corona [93][94]. The protein corona has a significant impact on how NPs interact with cells and thus will be discussed in the following in more detail. NPs can, in principle, be synthesized in water without any organic surface coating, for example by laser ablation [129][130][131]. However, also to NPs

The cell-type specific uptake of polymer-coated or micelle-embedded QDs and SPIOs does not provoke an acute pro-inflammatory response in the liver

• Markus Heine,
• Alexander Bartelt,
• Oliver T. Bruns,
• Denise Bargheer,
• Artur Giemsa,
• Barbara Freund,
• Ludger Scheja,
• Christian Waurisch,
• Alexander Eychmüller,
• Rudolph Reimer,
• Horst Weller,
• Peter Nielsen and
• Joerg Heeren

Beilstein J. Nanotechnol. 2014, 5, 1432–1440, doi:10.3762/bjnano.5.155

• the mononuclear phagocytic system (MPS) [7]. Consequently, larger nanocrystals are exposed to cellular degradation mechanisms of macrophages, e.g., the acidic environment of lysosomes and even more harsh conditions in phagosomes containing also hydrogen peroxide [8]. This might disrupt the surface

• coating and dissolve ions out of the inorganic crystal core. Such a degradation process will alter or diminish the optical properties of QDs and expose the cells and subsequently the whole body to toxic metal ions. Recently, the group of Bruchez described the changes in the optical properties of injected

PEGylated versus non-PEGylated magnetic nanoparticles as camptothecin delivery system

• Paula M. Castillo,
• Mario de la Mata,
• Maria F. Casula,
• José A. Sánchez-Alcázar and
• Ana P. Zaderenko

Beilstein J. Nanotechnol. 2014, 5, 1312–1319, doi:10.3762/bjnano.5.144

• ] is virtually absent from the spectrum. According to our FTIR data we may reasonably assume that the high succinic acid surface coating will translate into a high coating of PEG in the subsequent functionalization step. The FTIR spectrum, through the aforementioned symmetric stretching of the

Direct nanoscale observations of the coupled dissolution of calcite and dolomite and the precipitation of gypsum

• Francesco G. Offeddu,
• Jordi Cama,
• Josep M. Soler and
• Christine V. Putnis

Beilstein J. Nanotechnol. 2014, 5, 1245–1253, doi:10.3762/bjnano.5.138

• shorter in the calcite dissolution experiments. In the case of calcite dissolution in gypsum-equilibrated solutions, gypsum nucleation occurred immediately and surface coating was uniform all over the calcite surface, yielding a total calcite passivation. Arrow-shaped gypsum crystals evolved along the

Selective surface modification of lithographic silicon oxide nanostructures by organofunctional silanes

• Thomas Baumgärtel,
• Christian von Borczyskowski and
• Harald Graaf

Beilstein J. Nanotechnol. 2013, 4, 218–226, doi:10.3762/bjnano.4.22

• ) substrates with a self-assembled monolayer (SAM) of 1-dodecene molecules as a surface coating. The monolayer preparation was carried out in three steps: cleaning, native-oxide removal, and monolayer formation (radical chain reaction); see also [25][44]. The substrates have been cleaned by ultrasonication in

Nanostructure-directed chemical sensing: The IHSAB principle and the dynamics of acid/base-interface interaction

• James L. Gole and
• William Laminack

Beilstein J. Nanotechnol. 2013, 4, 20–31, doi:10.3762/bjnano.4.3

• microporous extrinsic semiconductor channels, through fractional deposition of the nanostructures. These nanostructures do not form a surface coating but rather act as independent nanostructured sites capable of strongly directed interaction with a given analyte and subsequent rapid electron transduction. In

• components are separable, they can be combined to provide an enhanced versatility versus a single or mixed metal-oxide surface coating. In concert with the IHSAB principle, this approach leads to an optimized and simpler interface. Treatment of the semiconductors with nanostructured photocatalysts can be

Functionalised zinc oxide nanowire gas sensors: Enhanced NO₂ gas sensor response by chemical modification of nanowire surfaces

• Eric R. Waclawik,
• Jin Chang,
• Andrea Ponzoni,
• Isabella Concina,
• Dario Zappa,
• Elisabetta Comini,
• Nunzio Motta,
• Guido Faglia and
• Giorgio Sberveglieri

Beilstein J. Nanotechnol. 2012, 3, 368–377, doi:10.3762/bjnano.3.43

• & Brescia University, Chemistry & Physics Department, Via Valotti 9, 25133 Brescia, Italy 10.3762/bjnano.3.43 Abstract Surface coating with an organic self-assembled monolayer (SAM) can enhance surface reactions or the absorption of specific gases and hence improve the response of a metal oxide (MOx

Superhydrophobic surfaces of the water bug Notonecta glauca: a model for friction reduction and air retention

• Petra Ditsche-Kuru,
• Erik S. Schneider,
• Jan-Erik Melskotte,
• Martin Brede,
• Alfred Leder and
• Wilhelm Barthlott

Beilstein J. Nanotechnol. 2011, 2, 137–144, doi:10.3762/bjnano.2.17

• them with a uniform hydrophobic surface coating. For that purpose the surfaces were dipped in Antispread (F2/200 Fluorcarbon 60, Horb-Ahldorf, Germany) for 10 s which forms approximately 40 nm thin layers on the substrate surfaces (product information). After drying for 30 minutes, the hydrophobized

Biomimetics inspired surfaces for drag reduction and oleophobicity/philicity

• Bharat Bhushan

Beilstein J. Nanotechnol. 2011, 2, 66–84, doi:10.3762/bjnano.2.9

• micropatterned surfaces, a flat Si surface and micropatterned Si surfaces with pillars of 14 μm diameter and 30 μm height with different pitch values (21, 23, 26, 35, 70, 105, 126, 168 and 210 μm), fabricated by photolithography, were used [20]. To study surfaces with some oleophobicity, a surface coating which

Magnetic nanoparticles for biomedical NMR-based diagnostics

• Huilin Shao,
• Tae-Jong Yoon,
• Monty Liong,
• Ralph Weissleder and
• Hakho Lee

Beilstein J. Nanotechnol. 2010, 1, 142–154, doi:10.3762/bjnano.1.17

• biocompatible surface coating that stabilizes the particle in physiological conditions. By applying suitable surface chemistry, functional ligands can be integrated and confer the MNP with molecular specificity. Synthesis of magnetic nanoparticles Synthetic methods for MNPs have been recently reviewed [15][16